ChemicalBook > CAS DataBase List > (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE

(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE

Product Name
(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
CAS No.
755039-55-5
Chemical Name
(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
Synonyms
6(5H)-pte;(7R)-2-Ch;BI-2536 parent nucleus;(7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-7H-pteridin-6-one;6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydr...;2-Chloro-8-cyclopentyl-7-ethyl-5-Methyl-7,8-dihydro-5H-pteridin-6-one;(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ON;(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE;(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydro-5H-pteridin-6-one;(7R)-2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-6(5H)-pteridinone
CBNumber
CB82454722
Molecular Formula
C14H19ClN4O
Formula Weight
294.78
MOL File
755039-55-5.mol
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(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Property

Boiling point:
537.5±45.0 °C(Predicted)
Density 
1.263±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
1.45±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

AK Scientific
Product number
1735AC
Product name
(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one
Packaging
100mg
Price
$275
Updated
2021/12/16
AK Scientific
Product number
1735AC
Product name
(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one
Packaging
250mg
Price
$410
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0032846
Product name
(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
Purity
95.00%
Packaging
5MG
Price
$495.13
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0032846
Product name
(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
Purity
95.00%
Packaging
1G
Price
$1253.7
Updated
2021/12/16
Matrix Scientific
Product number
122256
Product name
(7R)-2-Chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-methyl-6(5H)-pteridinone
Purity
97.0%
Packaging
1g
Price
$2344
Updated
2021/12/16
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(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Chemical Properties,Usage,Production

Synthesis

512-56-1

755039-54-4

755039-55-5

(7r)-2-Chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-6(5H)-pteridinone (260 mg, 0.93 mmol) was dissolved in dioxane (5 ml). Trimethyl phosphate (650 mg, 4.6 mmol) and potassium carbonate (192 mg, 1.39 mmol) were added and the reaction mixture was stirred at 90 °C for 6 hours until the ingredients were completely consumed. After completion of the reaction, the mixture was diluted with water and extracted with ethyl acetate. The organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (petroleum ether: ethyl acetate = 1:1) to afford (7R)-2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-methyl-6(5H)-pteridinone as a white solid (270 mg, 86% yield).1H NMR (CDCl3) δ: 7.7 (s 1H), 4.34 (m, 1H), 4.25 (m, 1H), 3.33 (s, 3H), 2.1-1.6 (m, 10H), 0.86 (t, 3H).

References

[1] Patent: WO2011/79114, 2011, A1. Location in patent: Page/Page column 54; 55

(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Suppliers

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View Lastest Price from (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE manufacturers

Career Henan Chemical Co
Product
(7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-7H-pteridin-6-one 755039-55-5
Price
US $3.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100kg
Release date
2019-07-10

755039-55-5, (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONERelated Search:

(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE 2-CHLORO-N4,N4-DIMETHYLPYRIMIDINE-4,5-DIAMINE 2-CHLORO-N,N-DIMETHYLPYRIMIDIN-5-AMINE 6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro 2-Chloro-8-methyl-7,8-dihydro-5H-pteridin-6-one 2-Chloro-pteridin

  • (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
  • 6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-, (7R)-
  • 2-Chloro-8-cyclopentyl-7-ethyl-5-Methyl-7,8-dihydro-5H-pteridin-6-one
  • (7R)-2-Ch
  • 6(5H)-pte
  • 6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-, (7R)- (7R)-2-Ch
  • (7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-5,6,7,8-tetrahydropteridin-6-one
  • (R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropyrimido[4,5-b]pyrazine
  • (7R)-2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-6(5H)-pteridinone
  • (R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydro-5H-pteridin-6-one
  • (7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-7H-pteridin-6-one
  • 6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydr...
  • BI-2536 parent nucleus
  • (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ON
  • 755039-55-5
  • 755035-55-5
  • C14H19ClN4O