ChemicalBook > CAS DataBase List > 5-BROMO-6-METHOXY (1H)INDAZOLE

5-BROMO-6-METHOXY (1H)INDAZOLE

Product Name
5-BROMO-6-METHOXY (1H)INDAZOLE
CAS No.
152626-78-3
Chemical Name
5-BROMO-6-METHOXY (1H)INDAZOLE
Synonyms
5-Bromo-6-methoxy indazole;5-BROMO-6-METHOXY (1H)INDAZOLE;1H-Indazole, 5-bromo-6-methoxy-;5-Bromo-6-methoxy-1H-indazole
CBNumber
CB82455138
Molecular Formula
C8H7BrN2O
Formula Weight
227.06
MOL File
152626-78-3.mol
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5-BROMO-6-METHOXY (1H)INDAZOLE Property

Boiling point:
363.4±22.0 °C(Predicted)
Density 
1.678±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
13.03±0.40(Predicted)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00190
Product name
5-Bromo-6-methoxy-1H-indazole
Purity
Aldrich
Packaging
1g
Price
$550
Updated
2025/07/31
TRC
Product number
B415505
Product name
5-Bromo-6-methoxy-1H-indazole
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
B415505
Product name
5-Bromo-6-methoxy-1H-indazole
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
B415505
Product name
5-Bromo-6-methoxy-1H-indazole
Packaging
500mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB41932
Product name
5-Bromo-6-methoxy-1H-indazole
Packaging
1g
Price
$205
Updated
2021/12/16
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5-BROMO-6-METHOXY (1H)INDAZOLE Chemical Properties,Usage,Production

Uses

5-bromo-6-methoxy-1H-indazole is a useful chemical for organic synthesis and reactions.

Synthesis

473417-48-0

152626-78-3

Step 2: Synthesis of 5-bromo-6-methoxy-1H-indazole (compound A33). 5-Bromo-2-fluoro-4-methoxybenzaldehyde (9 g, 38.6 mmol), o-hydroxylamine hydrochloride (3.23 g, 38.6 mmol) and potassium carbonate (5.87 g, 42.5 mmol) were dissolved in 1,2-dimethoxyethane (90 mL). The reaction mixture was stirred at 100 °C for 1 hour. After completion of the reaction, it was cooled to room temperature, the solids were removed by filtration and the filtrate was concentrated under reduced pressure. To the concentrate was added dimethylacetamide (90 mL) and hydrazine monohydrate (18 mL), and the mixture was stirred at 150 °C overnight. At the end of the reaction, it was cooled to room temperature, water was added to the reaction mixture and the aqueous layer was extracted with ethyl acetate. The organic layers were combined, washed sequentially with water and saturated aqueous sodium chloride and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give a yellow paste compound A33 (8.26 g, yield: 94%).ESI-MS m/z: 227,229 [M + H]+; 1H-NMR (300 MHz, CDCl3) δ (ppm): 3.96 (s, 3H), 6.92 (s, 1H), 7.94 (d, J=1.1 Hz, 2H).

References

[1] Patent: EP2308880, 2011, A1. Location in patent: Page/Page column 47

5-BROMO-6-METHOXY (1H)INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-6-METHOXY (1H)INDAZOLE Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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jkinfo@jkchemical.com
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China
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Beijing HwrkChemical Technology Co., Ltd
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Changzhou Wanyao Biotechnology Co., Ltd.
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View Lastest Price from 5-BROMO-6-METHOXY (1H)INDAZOLE manufacturers

Career Henan Chemical Co
Product
5-BROMO-6-METHOXY (1H)INDAZOLE 152626-78-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-03