5-BROMO-6-METHOXY (1H)INDAZOLE
- Product Name
- 5-BROMO-6-METHOXY (1H)INDAZOLE
- CAS No.
- 152626-78-3
- Chemical Name
- 5-BROMO-6-METHOXY (1H)INDAZOLE
- Synonyms
- 5-Bromo-6-methoxy indazole;5-BROMO-6-METHOXY (1H)INDAZOLE;1H-Indazole, 5-bromo-6-methoxy-;5-Bromo-6-methoxy-1H-indazole
- CBNumber
- CB82455138
- Molecular Formula
- C8H7BrN2O
- Formula Weight
- 227.06
- MOL File
- 152626-78-3.mol
5-BROMO-6-METHOXY (1H)INDAZOLE Property
- Boiling point:
- 363.4±22.0 °C(Predicted)
- Density
- 1.678±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 13.03±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SYX00190
- Product name
- 5-Bromo-6-methoxy-1H-indazole
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $550
- Updated
- 2025/07/31
- Product number
- B415505
- Product name
- 5-Bromo-6-methoxy-1H-indazole
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B415505
- Product name
- 5-Bromo-6-methoxy-1H-indazole
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B415505
- Product name
- 5-Bromo-6-methoxy-1H-indazole
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FB41932
- Product name
- 5-Bromo-6-methoxy-1H-indazole
- Packaging
- 1g
- Price
- $205
- Updated
- 2021/12/16
5-BROMO-6-METHOXY (1H)INDAZOLE Chemical Properties,Usage,Production
Uses
5-bromo-6-methoxy-1H-indazole is a useful chemical for organic synthesis and reactions.
Synthesis
473417-48-0
152626-78-3
Step 2: Synthesis of 5-bromo-6-methoxy-1H-indazole (compound A33). 5-Bromo-2-fluoro-4-methoxybenzaldehyde (9 g, 38.6 mmol), o-hydroxylamine hydrochloride (3.23 g, 38.6 mmol) and potassium carbonate (5.87 g, 42.5 mmol) were dissolved in 1,2-dimethoxyethane (90 mL). The reaction mixture was stirred at 100 °C for 1 hour. After completion of the reaction, it was cooled to room temperature, the solids were removed by filtration and the filtrate was concentrated under reduced pressure. To the concentrate was added dimethylacetamide (90 mL) and hydrazine monohydrate (18 mL), and the mixture was stirred at 150 °C overnight. At the end of the reaction, it was cooled to room temperature, water was added to the reaction mixture and the aqueous layer was extracted with ethyl acetate. The organic layers were combined, washed sequentially with water and saturated aqueous sodium chloride and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give a yellow paste compound A33 (8.26 g, yield: 94%).ESI-MS m/z: 227,229 [M + H]+; 1H-NMR (300 MHz, CDCl3) δ (ppm): 3.96 (s, 3H), 6.92 (s, 1H), 7.94 (d, J=1.1 Hz, 2H).
References
[1] Patent: EP2308880, 2011, A1. Location in patent: Page/Page column 47
5-BROMO-6-METHOXY (1H)INDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-6-METHOXY (1H)INDAZOLE manufacturers
- Product
- 5-BROMO-6-METHOXY (1H)INDAZOLE 152626-78-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-03