BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER
- Product Name
- BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER
- CAS No.
- 103440-54-6
- Chemical Name
- BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER
- Synonyms
- Methyl 5-iodo-2-Methylbenzoate;5-IODO-2-METHYL-, METHYL ESTER;Methyl 2-methyl-5-iodobenzoate;5-iodo-2-Methylbenzoic acid Methyl ester;BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER
- CBNumber
- CB82460095
- Molecular Formula
- C9H9IO2
- Formula Weight
- 276.07
- MOL File
- 103440-54-6.mol
BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER Property
- Melting point:
- 60℃
- Boiling point:
- 290.4±28.0 °C(Predicted)
- Density
- 1.666±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- crystalline needles
- color
- Off-white
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M262743
- Product name
- Methyl5-Iodo-2-methylbenzoate
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- OR42276
- Product name
- Methyl 5-iodo-2-methylbenzoate
- Packaging
- 1g
- Price
- $26
- Updated
- 2021/12/16
- Product number
- 2723-H-02
- Product name
- Methyl 5-iodo-2-methylbenzoate
- Packaging
- 2g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR42276
- Product name
- Methyl 5-iodo-2-methylbenzoate
- Packaging
- 5g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- Z1827
- Product name
- Methyl5-iodo-2-methylbenzoate
- Packaging
- 5g
- Price
- $183
- Updated
- 2021/12/16
BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER Chemical Properties,Usage,Production
Synthesis
67-56-1
54811-38-0
103440-54-6
General procedure for the synthesis of methyl 5-iodo-2-methylbenzoate from methanol and 5-iodo-2-methylbenzoic acid: Thionyl chloride (74 g, 0.62 mol) was added slowly and dropwise to a solution of 5-iodo-2-methylbenzoic acid (86 g, 0.57 mol) in methanol (0.5 L) at 0 °C. After the dropwise addition, the reaction mixture was heated to reflux and maintained for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure to remove the solvent. The concentrated residue was diluted with water and extracted with ethyl acetate (2 x 300 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, and finally concentrated under reduced pressure to afford the target product methyl 5-iodo-2-methylbenzoate (69 g, 73% yield), which could be used in subsequent reactions without further purification.
References
[1] Patent: WO2015/189744, 2015, A1. Location in patent: Page/Page column 73-74
[2] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 23, p. 6273 - 6278
[3] Patent: WO2006/117669, 2006, A1. Location in patent: Page/Page column 41; 115
BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
- Tel
- --
- Fax
- --
- enquiry@sldrugs.com
- Country
- India
- ProdList
- 2683
- Advantage
- 50
View Lastest Price from BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER manufacturers
- Product
- BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER 103440-54-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
- Product
- BENZOIC ACID, 5-IODO-2-METHYL-, METHYL ESTER 103440-54-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2020-03-05