(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Product Name: (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS No.: 141388-76-3
Chemical Name: (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Synonyms: Besivence;Besivance;Besifloxacin;Besifloxacin USP/EP/BP;Levetiracetam Impurity 50;3-Quinolinecarboxylicacid,7-[(3R)-3-aMinohexahydro-1H-azepin-1-y;7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid;(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-qu;(R)-7-(3-aMinoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;7-[(3R)-3-Amino-1-azepanyl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
CBNumber: CB82470922
Molecular Formula: C19H21ClFN3O3
Formula Weight: 393.84
MOL File: 141388-76-3.mol

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(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid Property

Boiling point:: 607.0±55.0 °C(Predicted)
Density: 1.469
storage temp.: Store at -20°C
solubility: DMSO: Insoluble;
pka: 6.41±0.50(Predicted)
Water Solubility: Water: Insoluble
InChI: InChI=1S/C19H21ClFN3O3/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23/h7,9-11H,1-6,8,22H2,(H,26,27)/t10-/m1/s1
InChIKey: QFFGVLORLPOAEC-SNVBAGLBSA-N
SMILES: N1(C2CC2)C2=C(C=C(F)C(N3CCCC[C@@H](N)C3)=C2Cl)C(=O)C(C(O)=O)=C1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 262103
Product name: Besifloxacin
Packaging: 500mg
Price: $694
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007091
Product name: BESIFLOXACIN
Purity: 95.00%
Packaging: 10G
Price: $1093.05
Updated: 2021/12/16

Matrix Scientific

Product number: 120837
Product name: (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylicacid
Purity: 97%
Packaging: 10g
Price: $1187
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 16846
Product name: Besifloxacin
Purity: 99%
Packaging: 50mg
Price: $1500
Updated: 2021/12/16

Matrix Scientific

Product number: 120837
Product name: (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylicacid
Purity: 97%
Packaging: 25g
Price: $2373
Updated: 2021/12/16

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(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Yellow to slightly yellow crystalline powder

Uses

Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity[1].

Definition

ChEBI: Besifloxacin is a member of quinolines.

Pharmaceutical Applications

An amino-azepinyl quinolone formulated as a suspension for ophthalmic usage. It exhibits good antistaphylococcal activity, as well as activity against Str. pneumoniae, Enterobacteriaceae, H. influenzae and Mor. catarrhalis. It is weakly active against Corynebacterium spp. and has no useful activity against Ps. aeruginosa. After instillation into the eye, less than 0.1% of the drug reaches the plasma. It is used for bacterial conjunctivitis.

IC 50

Quinolone

References

[1] Zhang JZ, et al. Besifloxacin, a novel fluoroquinolone antimicrobial agent, exhibits potent inhibition of pro-inflammatory cytokines in human THP-1 monocytes. J Antimicrob Chemother. 2008;61(1):111-116. DOI:10.1093/jac/dkm398

(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid Suppliers

China 45 India 3 United Kingdom 2 United States 7 Global 57

Hangzhou Hua Zhe Biological Medicine Co., LTD

Tel: 0571-5683-8096 17302275155
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Country: China
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Advantage: 58

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
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BOC Sciences

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Nanjing JinruiJiuAn Biotechnology Co., Ltd.

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Credit Asia Chemical Co., Ltd.

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LETOPHARM LIMITED

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Chizhou Kailong Import and Export Trade Co., Ltd.

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AN PharmaTech Co Ltd

Tel: 86(21)68097365
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Email: sales@anpharma.net
Country: China
ProdList: 4891
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parabiochem

Tel: 025-83453382-8005
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Email: sale@parabiochem.com
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View Lastest Price from (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid manufacturers

Hebei Mingeng Biotechnology Co., Ltd

Product: Besifloxacin 141388-76-3
Price: US $200.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg/Month
Release date: 2022-11-27

Shijiazhuang Gantuo Biotechnology Co., Ltd

Product: Besifloxacin 141388-76-3
Price: US $100.00/mg
Min. Order: 25mg
Purity: 99%
Supply Ability: 1000g
Release date: 2023-03-10

Dideu Industries Group Limited

Product: (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 141388-76-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-19

141388-76-3, (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acidRelated Search:

BEPOTASTINE Enoxacin

(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Besivence

Besifloxacin

Besivance

3-Quinolinecarboxylic acid, 7-[(3R)-3-aMinohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-

7-[(3R)-3-Amino-1-azepanyl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-qu

7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid

(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinolinecarboxylic acid

3-Quinolinecarboxylicacid,7-[(3R)-3-aMinohexahydro-1H-azepin-1-y

(R)-7-(3-aMinoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Besifloxacin USP/EP/BP

(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid USP/EP/BP

Levetiracetam Impurity 50

141388-76-3

C19H21ClFN3O3

APIs