ChemicalBook > CAS DataBase List > 2-Amino-3-hydroxy-5-chloropyridine

2-Amino-3-hydroxy-5-chloropyridine

Product Name
2-Amino-3-hydroxy-5-chloropyridine
CAS No.
40966-87-8
Chemical Name
2-Amino-3-hydroxy-5-chloropyridine
Synonyms
2-amino-5-chloro-3-pyridinol;2-anino-5-chloropyridin-3-ol;2-amino-5-chloropyridin-3-ol;3-Pyridinol, 2-amino-5-chloro-;2-Amino-5-chloro-3-hydroxypyridine;2-Amino-3-hydroxy-5-chloropyridine;2-Amino-5-chloro-3-hydroxypyridine 98%;2-Amino-3-hydroxy-5-chloropyridine ISO 9001:2015 REACH
CBNumber
CB82484882
Molecular Formula
C5H5ClN2O
Formula Weight
144.56
MOL File
40966-87-8.mol
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2-Amino-3-hydroxy-5-chloropyridine Property

Melting point:
198-201℃
Boiling point:
383.7±42.0 °C(Predicted)
Density 
1.516
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
11.48±0.10(Predicted)
form 
solid
color 
Brown
InChI
InChI=1S/C5H5ClN2O/c6-3-1-4(9)5(7)8-2-3/h1-2,9H,(H2,7,8)
InChIKey
BMRXXBXPVJOAMM-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(Cl)C=C1O
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Safety

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
36/37
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
A617608
Product name
2-Amino-5-chloropyridin-3-ol
Packaging
50mg
Price
$70
Updated
2021/12/16
TRC
Product number
A617608
Product name
2-Amino-5-chloropyridin-3-ol
Packaging
100mg
Price
$105
Updated
2021/12/16
TRC
Product number
A617608
Product name
2-Amino-5-chloropyridin-3-ol
Packaging
250mg
Price
$185
Updated
2021/12/16
Usbiological
Product number
415261
Product name
2-Amino-5-chloropyridin-3-ol
Packaging
25mg
Price
$305
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA152976
Product name
2-Amino-3-hydroxy-5-chloropyridine
Packaging
25mg
Price
$405
Updated
2021/12/16
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2-Amino-3-hydroxy-5-chloropyridine Chemical Properties,Usage,Production

Synthesis

35570-68-4

40966-87-8

Example 2: Sodium hydroxide (355 g, 8.883 mol) and deionized water (3.5 L) were added to a 50 L single-necked round-bottomed flask equipped with a magnetic stirrer. After the sodium hydroxide was completely dissolved, 6-chloro-oxazolo[4,5-b]pyridin-2(3H)-one (3.14 g, 0.018 mol) was added to the reaction system and a reflux condenser was installed. The reaction mixture was heated to reflux for 10 hours. The completion of the reaction was confirmed by thin layer chromatography (TLC) and gas chromatography (GC) monitoring. The pH of the reaction mixture was adjusted to 8 with 12 mol/L hydrochloric acid solution, at which point a large amount of precipitate was generated. The reaction mixture was filtered and the filter cake was washed with deionized water (400 mL) and dried to give the target product 2-amino-3-hydroxy-5-chloropyridine (420 g, 98% yield), which was analyzed by GC to be 97.9% pure. The melting point of the product was measured to be 197°C~202°C (literature value: 198°C~201°C).

References

[1] Patent: WO2018/37223, 2018, A1. Location in patent: Page/Page column 222; 223
[2] Patent: CN103755627, 2016, B. Location in patent: Paragraph 0024

2-Amino-3-hydroxy-5-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-3-hydroxy-5-chloropyridine Suppliers

Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
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China
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9310
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66
Adamas Reagent, Ltd.
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400-6009262 16621234537
Fax
021-64823266
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chenyj@titansci.com
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China
ProdList
14101
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59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
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China
ProdList
11035
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
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China
ProdList
42934
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Asset Chem-Tech Co., Ltd
Tel
15965823333
Fax
+86 (530) 562-1688
Country
China
ProdList
17
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62
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
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58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
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SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
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sales@shiyabiopharm.com
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China
ProdList
4169
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GIHI CHEMICALS CO.,LTD
Tel
0086-571-86217390
Fax
0086-571-86217391
Email
Sales@gihichem.com
Country
China
ProdList
860
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58
Suzhou Sino Rare Chemical Co., Ltd.
Tel
0512-62857507
Fax
+86-512-62857507
Email
sales@sinorarechem.com
Country
China
ProdList
991
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58
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View Lastest Price from 2-Amino-3-hydroxy-5-chloropyridine manufacturers

Dideu Industries Group Limited
Product
2-Amino-3-hydroxy-5-chloropyridine 40966-87-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-27
Career Henan Chemical Co
Product
2-Amino-3-hydroxy-5-chloropyridine 40966-87-8
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

40966-87-8, 2-Amino-3-hydroxy-5-chloropyridineRelated Search:


  • 2-Amino-3-hydroxy-5-chloropyridine
  • 2-amino-5-chloropyridin-3-ol
  • 2-anino-5-chloropyridin-3-ol
  • 2-Amino-5-chloro-3-hydroxypyridine
  • 2-Amino-5-chloro-3-hydroxypyridine 98%
  • 2-amino-5-chloro-3-pyridinol
  • 3-Pyridinol, 2-amino-5-chloro-
  • 2-Amino-3-hydroxy-5-chloropyridine ISO 9001:2015 REACH
  • 40966-87-8