ChemicalBook > CAS DataBase List > [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid

Product Name
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
CAS No.
378247-75-7
Chemical Name
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
Synonyms
Fmoc-7-aminocoumarin-4-acetic acid;Pyridine,2,3,6-trichloro-8-nitro-;N-Fmoc-Aminocoumarin-4-acetic acid;7-N-Fmoc-aminocoumarin-4-acetic acid;7-(Fmoc-amino)-2-oxo-2H-1-benzopyran-4-acetic acid;7-(9-Fluorenylmethyloxycarbonylamino)-coumarin-4-acetic acid;[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid;7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid;2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticaci;2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-
CBNumber
CB82489625
Molecular Formula
C26H19NO6
Formula Weight
441.43
MOL File
378247-75-7.mol
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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Property

Melting point:
273-276 °C
Boiling point:
660.5±55.0 °C(Predicted)
Density 
1.418±0.06 g/cm3(Predicted)
storage temp. 
Store at +2°C to +8°C.
pka
4.23±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
KMA0040
Product name
7-N-Fmoc-Aminocoumarin-4-aceticacid
Packaging
100mg
Price
$264
Updated
2021/12/16
Iris Biotech GmbH
Product number
RL-1170
Product name
Fmoc-ACA-OH
Packaging
1g
Price
$270
Updated
2021/12/16
AK Scientific
Product number
2787CS
Product name
2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticacid
Packaging
100mg
Price
$293
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA36373
Product name
7-N-Fmoc-Aminocoumarin-4-acetic acid
Packaging
500mg
Price
$300
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0078619
Product name
7-N-FMOC-AMINOCOUMARIN-4-ACETIC ACID
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Chemical Properties,Usage,Production

General Description

Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates. Fmoc-ACA-OH [1] must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled withy HATU/collidine [2]. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases [3]. Treatment of the ACC peptide obtained after TFA cleavage with aqueous base causes facile decarboxylation and formation of the AMC peptide.

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Preparation Products And Raw materials

Raw materials

Preparation Products

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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Suppliers

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378247-75-7, [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacidRelated Search:


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