ChemicalBook > CAS DataBase List > [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
- Product Name
- [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
- CAS No.
- 378247-75-7
- Chemical Name
- [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
- Synonyms
- Fmoc-7-aminocoumarin-4-acetic acid;Pyridine,2,3,6-trichloro-8-nitro-;N-Fmoc-Aminocoumarin-4-acetic acid;7-N-Fmoc-aminocoumarin-4-acetic acid;7-(Fmoc-amino)-2-oxo-2H-1-benzopyran-4-acetic acid;7-(9-Fluorenylmethyloxycarbonylamino)-coumarin-4-acetic acid;[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid;7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid;2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticaci;2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-
- CBNumber
- CB82489625
- Molecular Formula
- C26H19NO6
- Formula Weight
- 441.43
- MOL File
- 378247-75-7.mol
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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Property
- Melting point:
- 273-276 °C
- Boiling point:
- 660.5±55.0 °C(Predicted)
- Density
- 1.418±0.06 g/cm3(Predicted)
- storage temp.
- Store at +2°C to +8°C.
- pka
- 4.23±0.10(Predicted)
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N-Bromosuccinimide Price
AK Scientific
- Product number
- KMA0040
- Product name
- 7-N-Fmoc-Aminocoumarin-4-aceticacid
- Packaging
- 100mg
- Price
- $264
- Updated
- 2021/12/16
Iris Biotech GmbH
- Product number
- RL-1170
- Product name
- Fmoc-ACA-OH
- Packaging
- 1g
- Price
- $270
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2787CS
- Product name
- 2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticacid
- Packaging
- 100mg
- Price
- $293
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA36373
- Product name
- 7-N-Fmoc-Aminocoumarin-4-acetic acid
- Packaging
- 500mg
- Price
- $300
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0078619
- Product name
- 7-N-FMOC-AMINOCOUMARIN-4-ACETIC ACID
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Chemical Properties,Usage,Production
General Description
Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates. Fmoc-ACA-OH [1] must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled withy HATU/collidine [2]. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases [3]. Treatment of the ACC peptide obtained after TFA cleavage with aqueous base causes facile decarboxylation and formation of the AMC peptide.
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Preparation Products And Raw materials
Raw materials
Preparation Products
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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Suppliers
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