ChemicalBook > CAS DataBase List > N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
- Product Name
- N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
- CAS No.
- 918505-61-0
- Chemical Name
- N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
- Synonyms
- CS-1029;PLX 4032;INXN-1001;ZELBORAF.(R).;BRAF inhibitor;PLX-4032(RG7204);Vemurafenib-Analog;Raf kinases,inhibit,Inhibitor,BRAF inhibitor,Raf;N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin...;N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide
- CBNumber
- CB82489948
- Molecular Formula
- C22H18F2N4O3S
- Formula Weight
- 456.47
- MOL File
- 918505-61-0.mol
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N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Property
- Density
- 1.45
- storage temp.
- Store at -20°C
- solubility
- DMSO : 50 mg/mL (109.54 mM; Need ultrasonic)
- form
- Powder
- pka
- 6.54±0.10(Predicted)
- color
- White to off-white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Biosynth Carbosynth
- Product number
- FV15248
- Product name
- PLX 4032
- Packaging
- 50mg
- Price
- $75
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FV15248
- Product name
- PLX 4032
- Packaging
- 100mg
- Price
- $100
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0055
- Product name
- BRAFinhibitor
- Purity
- 98.61%
- Packaging
- 10mg
- Price
- $180
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FV15248
- Product name
- PLX 4032
- Packaging
- 250mg
- Price
- $187.5
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A3263
- Product name
- BRAFinhibitor
- Packaging
- 10mg
- Price
- $293
- Updated
- 2021/12/16
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N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Chemical Properties,Usage,Production
Uses
Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Potent B-Raf inhibitor
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Preparation Products And Raw materials
Raw materials
Preparation Products
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N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
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View Lastest Price from N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide manufacturers
Career Henan Chemical Co
- Product
- N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide 918505-61-0
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08