ChemicalBook > CAS DataBase List > 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine

Product Name
5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine
CAS No.
1111638-02-8
Chemical Name
5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine
Synonyms
2-Methyl-5-bromo-7-azaindole;5-Bromo-2-methyl-7-Azaind...;5-Bromo-2-methyl-7-Azaindole;5-Bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine;5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2-Methyl-
CBNumber
CB82489968
Molecular Formula
C8H7BrN2
Formula Weight
211.06
MOL File
1111638-02-8.mol
More
Less

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Property

Density 
1.654
storage temp. 
Sealed in dry,Room Temperature
pka
13.49±0.40(Predicted)
form 
powder
color 
Yellow
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-41
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE001093
Product name
5-Bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine
Purity
Aldrich<SUP>CPR</SUP>
Packaging
1 g
Price
$1030
Updated
2025/07/31
Sigma-Aldrich
Product number
ADE001092
Product name
5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine
Purity
Aldrich
Packaging
1g
Price
$1030
Updated
2025/07/31
TRC
Product number
B697663
Product name
5-Bromo-2-methyl-1h-pyrrolo[2,3-b]pyridine
Packaging
50mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
059416
Product name
5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine
Packaging
250mg
Price
$115
Updated
2021/12/16
Matrix Scientific
Product number
059416
Product name
5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine
Packaging
500mg
Price
$205
Updated
2021/12/16
More
Less

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Chemical Properties,Usage,Production

Synthesis

1111638-01-7

1111638-02-8

Preparation of Method A Steps for the synthesis of intermediate 4: 5-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine: Ingredient 3 (88 mg, 0.251 mmol) was dissolved in methanol (4 mL), 2 N sodium hydroxide solution (1 mL) was added, and the reaction mixture was heated and refluxed for 2 hours. After completion of the reaction, ethyl acetate was added for extraction and the organic phase was washed sequentially with 1 N sodium hydroxide solution and water. Purification by silica gel column chromatography (slow gradient elution, volume fraction of methanol in dichloromethane increased from 0% to 2%) afforded the target product 4 (40 mg, 0.19 mmol, 76% yield). Product characterization data were as follows: 1H NMR (CDCl3, 300 MHz): δ 10.26 (br s, 1H), 8.22 (d, J = 2.1 Hz, 1H), 8.92 (d, J = 2.1 Hz, 1H), 6.13 (s, 1H), 2.52 (s, 3H). MS (m/z): 210 (M + H).

References

[1] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 5, p. 582 - 586
[2] Patent: WO2011/149950, 2011, A2. Location in patent: Page/Page column 151-152
[3] Patent: WO2014/85795, 2014, A1. Location in patent: Paragraph 0394
[4] Bioorganic Chemistry, 2016, vol. 65, p. 146 - 158
[5] Patent: WO2009/16460, 2009, A2. Location in patent: Page/Page column 74

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine Suppliers

China 81 India 1 Ukraine 1 United Kingdom 1 United States 17 Global 101
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
MolBridge
Tel
--
Fax
--
Email
sales@molbridge.com
Country
United States
ProdList
115
Advantage
38
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynChem，Inc
Tel
--
Fax
--
Email
sales@synchem.com
Country
United States
ProdList
4697
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Aroma Circle Corp.
Tel
--
Fax
--
Email
sales@aromacircle.com
Country
United States
ProdList
75
Advantage
50
ECA International Corporation
Tel
--
Fax
--
Email
services@ecacorporation.com
Country
United States
ProdList
1062
Advantage
52
AstaTech, Inc
Tel
--
Fax
--
Email
sales@astatechinc.com
Country
United States
ProdList
6371
Advantage
58
Aces Pharma, Inc.
Tel
--
Fax
--
Email
sales@acespharma.com
Country
United States
ProdList
959
Advantage
50
NOVASYN ORGANICS PVT LTD
Tel
--
Fax
--
Email
info@novasynorganics.com
Country
United States
ProdList
1316
Advantage
55
More
Less

View Lastest Price from 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine manufacturers

Career Henan Chemical Co
Product
5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine 1111638-02-8
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

1111638-02-8, 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridineRelated Search:

5-bromo-2-methyl-3H-imidazo[4,5-b]pyridine 5-BROMO-2-METHYL-4(1H)-PYRIMIDINONE 5-BROMO-2-METHYLNICOTINIC ACID Methyl 5-broMo-2-MethylpyriMidine-4-carboxylate 5-BROMO-2-METHYLBENZODOXAZOLE METHYL 5-BROMO-2-METHOXYNICOTINATE 5-Bromo-2-methylpyrimidine-4-carboxylic acid ethyl ester 5-Bromo-3-cyano-2-methoxypyridine 5-BROMO-2-METHOXY-NICOTINIC ACID 5-BroMo-2-Methylnicotinonitrile 5-Bromo-2-methyl-2H-indazole-3-carbaldehyde 5-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE

  • 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine
  • 5-Bromo-2-methyl-7-Azaindole
  • 5-Bromo-2-methyl-7-Azaind...
  • 5-Bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine
  • 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2-Methyl-
  • 2-Methyl-5-bromo-7-azaindole
  • 1111638-02-8
  • Azaindoles