ChemicalBook > CAS DataBase List > 2-Amino-3-bromo-6-chloropyrazine

2-Amino-3-bromo-6-chloropyrazine

Product Name
2-Amino-3-bromo-6-chloropyrazine
CAS No.
212779-21-0
Chemical Name
2-Amino-3-bromo-6-chloropyrazine
Synonyms
104365;2-Amino-3-bromo-6-chL;3-Bromo-6-chloro-2-pyrazinamine;2-Amino-3-bromo-6-chloropyrazine;2-PyrazinaMine, 3-broMo-6-chloro-;3-Bromo-6-chloro-pyrazin-2-ylamine;2-Amino-3-bromo-6-chloropyrazine ISO 9001：2015 REACH
CBNumber
CB82500753
Molecular Formula
C4H3BrClN3
Formula Weight
208.44
MOL File
212779-21-0.mol
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2-Amino-3-bromo-6-chloropyrazine Property

Boiling point:
299.5±35.0 °C(Predicted)
Density 
1.960
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
0.05±0.10(Predicted)
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C4H3BrClN3/c5-3-4(7)9-2(6)1-8-3/h1H,(H2,7,9)
InChIKey
BOLCKGGORFPPJC-UHFFFAOYSA-N
SMILES
C1(N)=NC(Cl)=CN=C1Br
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A594275
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
100mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
414996
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
100mg
Price
$305
Updated
2021/12/16
AK Scientific
Product number
J96339
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
1g
Price
$25
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA75138
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
10g
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA75138
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
25g
Price
$500
Updated
2021/12/16
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2-Amino-3-bromo-6-chloropyrazine Chemical Properties,Usage,Production

Uses

2-amino-3-bromo-6-chloropyrazine has essential applications in the pharmaceutical industry and is an important intermediate for synthesizing an anti-tumor medicament SHP2 inhibitor.

Preparation

Currently, in thepreparing 2-amino-3-bromo-6-chloropyrazine, the 2-amino-6-chloropyrazine is mainly obtained by a one-step bromination reaction. According to the method, bromine is mainly positioned at an amino para position due to the activation effect of amino; generated byproducts are mainly 2-bromo-3-chloro-5-aminopyrazine and partial dibromo byproduct 2-amino-3, 5-dibromo-6-chloropyrazine, the product 2-amino-3-bromo-6-chloro is less, the yield is low. A process for preparing 2-amino-3-bromo-6-chloropyrazine uses 3-aminopyrazine-2-carboxylate as raw material and includes such steps as chlorination, diazotization bromination, ester hydrolysis, carboxyl rearrangement and removing tert-butyloxycarbonyl.

2-Amino-3-bromo-6-chloropyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-3-bromo-6-chloropyrazine Suppliers

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View Lastest Price from 2-Amino-3-bromo-6-chloropyrazine manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
2-Amino-3-bromo-6-chloropyrazine 212779-21-0
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-14
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
3-bromo-6-chloropyrazin-2-amine 212779-21-0
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10KG
Release date
2021-09-16
Career Henan Chemical Co
Product
2-Amino-3-bromo-6-chloropyrazine 212779-21-0
Price
US $6.00/KG
Min. Order
1KG
Purity
95%-98%
Supply Ability
100
Release date
2019-09-04

212779-21-0, 2-Amino-3-bromo-6-chloropyrazineRelated Search:

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  • 3-Bromo-6-chloro-2-pyrazinamine
  • 3-Bromo-6-chloro-pyrazin-2-ylamine
  • 2-Amino-3-bromo-6-chloropyrazine
  • 2-Amino-3-bromo-6-chL
  • 2-Amino-3-bromo-6-chloropyrazine ISO 9001：2015 REACH
  • 212779-21-0