2-Bromo-1-bromomethyl-5-chlorobenzene
- Product Name
- 2-Bromo-1-bromomethyl-5-chlorobenzene
- CAS No.
- 66192-24-3
- Chemical Name
- 2-Bromo-1-bromomethyl-5-chlorobenzene
- Synonyms
- 2-Bromo-1-bromomethyl-5-chlorobenzene;Benzene, 1-bromo-2-(bromomethyl)-4-chloro-
- CBNumber
- CB82502904
- Molecular Formula
- C7H5Br2Cl
- Formula Weight
- 284.38
- MOL File
- 66192-24-3.mol
2-Bromo-1-bromomethyl-5-chlorobenzene Property
- Melting point:
- 63-64°C
- Boiling point:
- 281.5±25.0 °C(Predicted)
- Density
- 1.933
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- color
- White
- InChI
- InChI=1S/C7H5Br2Cl/c8-4-5-3-6(10)1-2-7(5)9/h1-3H,4H2
- InChIKey
- UTKGZXVMMFBCJC-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC=C(Cl)C=C1CBr
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B680600
- Product name
- 2-Bromo-1-bromomethyl-5-chlorobenzene
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB19053
- Product name
- 2-Bromo-1-bromomethyl-5-chlorobenzene
- Packaging
- 50g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- FB19053
- Product name
- 2-Bromo-1-bromomethyl-5-chlorobenzene
- Packaging
- 100g
- Price
- $152
- Updated
- 2021/12/16
- Product number
- FB19053
- Product name
- 2-Bromo-1-bromomethyl-5-chlorobenzene
- Packaging
- 25g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB19053
- Product name
- 2-Bromo-1-bromomethyl-5-chlorobenzene
- Packaging
- 250g
- Price
- $305
- Updated
- 2021/12/16
2-Bromo-1-bromomethyl-5-chlorobenzene Chemical Properties,Usage,Production
Chemical Properties
Colourless Oil
Synthesis
14495-51-3
66192-24-3
The general procedure for the synthesis of 2-bromo-5-chlorobenzyl bromide from 2-bromo-5-chlorotoluene was as follows: 20.5 g (100 mmol) of 2-bromo-5-chlorotoluene was dissolved in 200 mL of carbon tetrachloride, followed by the addition of 0.2 g (1 mmol) of AIBN (azobisisobutyronitrile) and 19.6 g (110 mmol) of N-bromosuccinimide (NBS). The resulting mixture was refluxed for 2 h and then cooled to room temperature. The reaction mixture was sequentially washed twice with 50 mL of water, then with 50 mL of brine solution and finally dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure to give an oil containing a small amount of unreacted material. The oily substance was dissolved in 20 mL of hexane and recrystallized at room temperature to give 22.7 g (80% yield) of 2-bromo-1-bromomethyl-5-chlorobenzene. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 7.50 (d, 1H, J = 8.7 Hz), 7.45 (d, 1H, J = 2.4 Hz), 7.15 (dd, 1H, J = 8.7 Hz, 2.4 Hz), 4.53 (s, 2H).
References
[1] Organic and Biomolecular Chemistry, 2012, vol. 10, # 31, p. 6404 - 6409
[2] Patent: WO2005/123054, 2005, A1. Location in patent: Page/Page column 25
[3] Patent: WO2006/46030, 2006, A2. Location in patent: Page/Page column 28
[4] Organic Letters, 2015, vol. 17, # 19, p. 4654 - 4657
[5] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 19, p. 2903 - 2909
2-Bromo-1-bromomethyl-5-chlorobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-1-bromomethyl-5-chlorobenzene Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
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View Lastest Price from 2-Bromo-1-bromomethyl-5-chlorobenzene manufacturers
- Product
- 1-Bromo-2-(bromomethyl)-4-chlorobenzene 66192-24-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-11
- Product
- 2-Bromo-1-bromomethyl-5-chlorobenzene 66192-24-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-17
- Product
- 2-Bromo-1-bromomethyl-5-chlorobenzene 66192-24-3
- Price
- US $80.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-27