ChemicalBook > CAS DataBase List > 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

Product Name: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
CAS No.: 927871-76-9
Chemical Name: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Synonyms: S107;CS-2452;S-107,S107;S-107; S 10;S107 free base;S 107 hydrochloride;S107, 10 mM in DMSO;2,3,4,5-Tetrahydro-7-methoxy-4-methyl-;RyR-Calstabin Interaction Stabilizer, S107;7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine
CBNumber: CB82506371
Molecular Formula: C11H15NOS
Formula Weight: 209.31
MOL File: 927871-76-9.mol

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2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Property

Boiling point:: 318.8±42.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 100mg/mL
form: Solid
pka: 7.74±0.20(Predicted)
color: White to off-white
Water Solubility: Water : ≥ 132 mg/mL (537.09 mM)
BRN: 18342799

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.00469
Product name: RyR-Calstabin Interaction Stabilizer, S107
Packaging: 10 mg
Price: $212
Updated: 2025/07/31

AK Scientific

Product number: 1331AH
Product name: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Packaging: 5mg
Price: $96
Updated: 2021/12/16

AK Scientific

Product number: 1331AH
Product name: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Packaging: 100mg
Price: $163
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1046160
Product name: 2,3,4,5-TETRAHYDRO-7-METHOXY-4-METHYL-1,4-BENZOTHIAZEPINE
Purity: 95.00%
Packaging: 5MG
Price: $495.48
Updated: 2021/12/16

AK Scientific

Product number: 1331AH
Product name: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Packaging: 1g
Price: $577
Updated: 2021/12/16

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2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Chemical Properties,Usage,Production

Uses

It is a benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance.

Biological Activity

Primary Target
RyR2

in vivo

S107, which prevents a leak in the channel but does not block the channel or alter normal Ca²⁺ signaling, is able to inhibit both seizures and arrhythymias in the mutant mice^[1].

2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine manufacturers

Career Henan Chemical Co

Product: 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine 927871-76-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

927871-76-9, 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepineRelated Search:

2,2-DIMETHYLTETRAHYDROFURAN N-Methyldiethanolamine

2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

S-107; S 10

CS-2452

7-methoxy-4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine

2,3,4,5-Tetrahydro-7-methoxy-4-methyl-

S 107 hydrochloride

S107

1,4-Benzothiazepine, 2,3,4,5-tetrahydro-7-methoxy-4-methyl-

S107 free base

S-107,S107

7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine

S107, 10 mM in DMSO

RyR-Calstabin Interaction Stabilizer, S107

927871-76-9

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