ChemicalBook > CAS DataBase List > 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine

Product Name
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
CAS No.
927871-76-9
Chemical Name
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Synonyms
S107;CS-2452;S-107,S107;S-107; S 10;S107 free base;S 107 hydrochloride;S107, 10 mM in DMSO;2,3,4,5-Tetrahydro-7-methoxy-4-methyl-;RyR-Calstabin Interaction Stabilizer, S107;7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine
CBNumber
CB82506371
Molecular Formula
C11H15NOS
Formula Weight
209.31
MOL File
927871-76-9.mol
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2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Property

Boiling point:
318.8±42.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 100mg/mL
form 
Solid
pka
7.74±0.20(Predicted)
color 
White to off-white
Water Solubility 
Water : ≥ 132 mg/mL (537.09 mM)
BRN 
18342799
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
1331AH
Product name
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Packaging
5mg
Price
$96
Updated
2021/12/16
AK Scientific
Product number
1331AH
Product name
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Packaging
100mg
Price
$163
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1046160
Product name
2,3,4,5-TETRAHYDRO-7-METHOXY-4-METHYL-1,4-BENZOTHIAZEPINE
Purity
95.00%
Packaging
5MG
Price
$495.48
Updated
2021/12/16
AK Scientific
Product number
1331AH
Product name
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Packaging
1g
Price
$577
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
61995
Product name
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
Packaging
10mg
Price
$640
Updated
2021/12/16
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2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Chemical Properties,Usage,Production

Uses

It is a benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance.

Biological Activity

Primary Target
RyR2

2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine manufacturers

Career Henan Chemical Co
Product
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine 927871-76-9
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

927871-76-9, 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepineRelated Search:


  • 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
  • S-107; S 10
  • CS-2452
  • 7-methoxy-4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine
  • 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-
  • S 107 hydrochloride
  • S107
  • 1,4-Benzothiazepine, 2,3,4,5-tetrahydro-7-methoxy-4-methyl-
  • S107 free base
  • S-107,S107
  • 7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine
  • S107, 10 mM in DMSO
  • RyR-Calstabin Interaction Stabilizer, S107
  • 927871-76-9
  • API