2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
- Product Name
- 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
- CAS No.
- 927871-76-9
- Chemical Name
- 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
- Synonyms
- S107;CS-2452;S-107,S107;S-107; S 10;S107 free base;S 107 hydrochloride;S107, 10 mM in DMSO;2,3,4,5-Tetrahydro-7-methoxy-4-methyl-;RyR-Calstabin Interaction Stabilizer, S107;7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine
- CBNumber
- CB82506371
- Molecular Formula
- C11H15NOS
- Formula Weight
- 209.31
- MOL File
- 927871-76-9.mol
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Property
- Boiling point:
- 318.8±42.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 100mg/mL
- form
- Solid
- pka
- 7.74±0.20(Predicted)
- color
- White to off-white
- Water Solubility
- Water : ≥ 132 mg/mL (537.09 mM)
- BRN
- 18342799
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 5.00469
- Product name
- RyR-Calstabin Interaction Stabilizer, S107
- Packaging
- 10 mg
- Price
- $212
- Updated
- 2025/07/31
- Product number
- 1331AH
- Product name
- 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
- Packaging
- 5mg
- Price
- $96
- Updated
- 2021/12/16
- Product number
- 1331AH
- Product name
- 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
- Packaging
- 100mg
- Price
- $163
- Updated
- 2021/12/16
- Product number
- CHM1046160
- Product name
- 2,3,4,5-TETRAHYDRO-7-METHOXY-4-METHYL-1,4-BENZOTHIAZEPINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.48
- Updated
- 2021/12/16
- Product number
- 1331AH
- Product name
- 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine
- Packaging
- 1g
- Price
- $577
- Updated
- 2021/12/16
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Chemical Properties,Usage,Production
Uses
It is a benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance.
Biological Activity
Primary Target
RyR2
in vivo
S107, which prevents a leak in the channel but does not block the channel or alter normal Ca2+ signaling, is able to inhibit both seizures and arrhythymias in the mutant mice[1].
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Preparation Products And Raw materials
Raw materials
Preparation Products
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine manufacturers
- Product
- 2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine 927871-76-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2019-12-23