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Paliperidone Palmitate

Product Name
Paliperidone Palmitate
CAS No.
199739-10-1
Chemical Name
Paliperidone Palmitate
Synonyms
Invega Sustenna;RO 92670;Paliperidone Palmitate;Paliperidone Palmitate-d31;Paliperidone Palmitate [USAN];9-Hydroxyrisperidone palmitate;Palmitone Palmitate Impurity 4;Palmitone Palmitate Impurity 6;Palmitone Palmitate Impurity 3;Palmitone Palmitate Impurity 2
CBNumber
CB82519012
Molecular Formula
C39H57FN4O4
Formula Weight
664.89
MOL File
199739-10-1.mol
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Paliperidone Palmitate Property

Melting point:
110-115°C
Boiling point:
736.3±70.0 °C(Predicted)
Density 
1.19
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated, Sonicated), Methanol (Slightly)
form 
Solid
pka
8.07±0.10(Predicted)
color 
Off-White to Light Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
P141020
Product name
PaliperidonePalmitate
Packaging
500mg
Price
$210
Updated
2021/12/16
Activate Scientific
Product number
AS148096
Product name
PaliperidonePalmitate
Purity
98%
Packaging
250mg
Price
$233
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0027470
Product name
PALIPERIDONE PALMITATE
Purity
95.00%
Packaging
25MG
Price
$750.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0027470
Product name
PALIPERIDONE PALMITATE
Purity
95.00%
Packaging
250MG
Price
$1963.5
Updated
2021/12/16
ChemScene
Product number
CS-0016387
Product name
Paliperidonepalmitate
Purity
98.16%
Packaging
10mg
Price
$70
Updated
2021/12/16
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Paliperidone Palmitate Chemical Properties,Usage,Production

Description

Paliperidone palmitate is an atypical long acting antipsychotics,which can fast onset in acute phase and continuously improve the symptoms in maintenance phase. It has the solid efficacy and convenient ad[1]ministration,which offer a new option for schizophrenia treatment and will help patients to adhere the treatment and prevent relapse. As the sole long acting antipsychotics with monthly injection,it was approved by CFDA in 2011 and indicated for the acute and maintenance treatment of schizophrenia.

Uses

Paliperidone Palmitate is a long-acting injectable atypical antipsychotic used in the treatment of schizophrenia.

Definition

ChEBI: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl hexadecanoate is a fatty acid ester obtained by the formal condensation of the carboxy group of hexadecanoic acid with the hydroxy group of 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one. It is a member of 1,2-benzoxazoles, a heteroarylpiperidine, an organofluorine compound, a pyridopyrimidine and a fatty acid ester.

Side effects

The review of the literature also underlined that paliperidone palmitate is well tolerated, compared with placebo. Frequency and severity of side-effects such as extrapyramidal symptoms, hyperprolactinemia and weight gain, was similar or less than those found in treatment with other atypical antipsychotics, including long-acting ones.

Paliperidone Palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

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Paliperidone Palmitate Suppliers

Zhuzhou focus pharmaceutical technology co., LTD
Tel
+86-13776644403
Email
robert@focuspharma.cc
Country
China
ProdList
2300
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
18502762009
Email
721846333@qq.com
Country
China
ProdList
2448
Advantage
58
Henan Dongyao Pharmaceutical Technology Co., Ltd
Tel
18519331287
Email
1751713684@qq.com
Country
China
ProdList
203
Advantage
58
Jilin Lianben Technology Development Co., Ltd
Tel
13756693631
Fax
0432-62601618
Email
sunting@lianben.com
Country
China
ProdList
46
Advantage
58
Beijing Yusheng Chemical Co., Ltd.
Tel
17777863707
Email
17777863707@189.cn
Country
China
ProdList
500
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
Advantage
57
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Beijing Lunarsun Pharmaceutical Co.,LTD.
Tel
86-10-64911848-8020.8010
Fax
86-10-64946614
Email
sales@lunarsun.com.cn
Country
China
ProdList
95
Advantage
60
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View Lastest Price from Paliperidone Palmitate manufacturers

Sinoway Industrial co., ltd.
Product
Paliperidone Palmitate 199739-10-1
Price
US $0.00-0.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
0.99
Supply Ability
20 tons
Release date
2024-06-27
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Paliperidone Palmitate 199739-10-1
Price
US $0.00/g
Min. Order
100g
Purity
98.0%
Supply Ability
50kg/month
Release date
2021-07-23
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Paliperidone Palmitate 199739-10-1
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-09-20

199739-10-1, Paliperidone PalmitateRelated Search:


  • (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)et hyl)-2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyriMi din-9-yl hexadecanoate
  • Hexadecanoic acid 3-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]-ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester
  • Paliperidone Palmitate
  • Paliperidone Palmitate [USAN]
  • Invega Sustenna
  • RO 92670
  • 9-Hydroxyrisperidone palmitate
  • Hexadecanoic acid 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester
  • Paliperidone Palmitate-d31
  • Paliperidone Impurity 39 (Paliperidone Palmitate)
  • 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate
  • Paliperidone Palmitate USP/EP/BP
  • Paliperidone palmitateQ: What is Paliperidone palmitate Q: What is the CAS Number of Paliperidone palmitate Q: What is the storage condition of Paliperidone palmitate Q: What are the applications of Paliperidone palmitate
  • Palmitic acid paliperidone impurity
  • Palmitic acid paliperidone standard
  • Paliperidone Palmitate Benzisoxazole Impurity
  • Palmitone Palmitate Impurity 4
  • Palmitone Palmitate Impurity 6
  • Palmitone Palmitate Impurity 3
  • Palmitone Palmitate Impurity 2
  • Palmitic acid paliperidone impurity 3
  • Palmitic acid paliperidone impurity 1
  • Palmitic acid paliperidone impurity 5
  • Palmitic acid paliperidone impurity 2
  • Palmitone Palmitate Impurity 5
  • Palmitic acid paliperidone impurity 4
  • 199739-10-1
  • C39H57FN4O4
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API