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1-Boc-1H-pyrrolo[3,2-c]pyridine

Product Name
1-Boc-1H-pyrrolo[3,2-c]pyridine
CAS No.
148760-75-2
Chemical Name
1-Boc-1H-pyrrolo[3,2-c]pyridine
Synonyms
1-Boc-1H-pyrrolo[3,2-c]pyridine;1-Boc-pyrrolo[3,2-c]pyridine, 95%;1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester;1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 1,1-diMethylethyl ester
CBNumber
CB82533920
Molecular Formula
C12H14N2O2
Formula Weight
218.25
MOL File
148760-75-2.mol
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1-Boc-1H-pyrrolo[3,2-c]pyridine Property

Boiling point:
339.3±34.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
7.02±0.30(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B810118
Product name
tert-Butyl1H-Pyrrolo[3,2-c]pyridine-1-carboxylate
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
B810118
Product name
tert-Butyl1H-Pyrrolo[3,2-c]pyridine-1-carboxylate
Packaging
100mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
126747
Product name
tert-Butyl1H-pyrrolo[3,2-c]pyridine-1-carboxylate
Purity
>95%
Packaging
1g
Price
$258
Updated
2021/12/16
AK Scientific
Product number
7415AA
Product name
tert-Butyl1H-pyrrolo[3,2-c]pyridine-1-carboxylate
Packaging
10g
Price
$584
Updated
2021/12/16
Matrix Scientific
Product number
126747
Product name
tert-Butyl1H-pyrrolo[3,2-c]pyridine-1-carboxylate
Purity
>95%
Packaging
5g
Price
$892
Updated
2021/12/16
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1-Boc-1H-pyrrolo[3,2-c]pyridine Chemical Properties,Usage,Production

Synthesis

271-34-1

24424-99-5

148760-75-2

Step A: Preparation of tert-butyl 1H-pyrrolo[3,2-c]pyridine-1-carboxylate: To a stirred mixture of 5-azaindole (2.3 g, 20 mmol) and 4-dimethylaminopyridine (2.4 g, 20 mmol) in acetonitrile (20 mL) was added di-tert-butyl dicarbonate (3.9 g, 18 mmol). The reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure and subsequently purified by Biotage Flash 40S column chromatography using 1:1 ethyl acetate/hexane as eluent. The target product 1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester was obtained as a colorless oil (4.0 g, 101% yield).

References

[1] Patent: US2007/238726, 2007, A1. Location in patent: Page/Page column 114
[2] Patent: WO2017/23987, 2017, A1. Location in patent: Paragraph 0703; 0704
[3] Patent: WO2017/24003, 2017, A1. Location in patent: Paragraph 0703; 0704
[4] Patent: WO2017/24010, 2017, A1. Location in patent: Paragraph 0650; 0651
[5] Patent: WO2017/23984, 2017, A1. Location in patent: Paragraph 0703

1-Boc-1H-pyrrolo[3,2-c]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Boc-1H-pyrrolo[3,2-c]pyridine Suppliers

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148760-75-2, 1-Boc-1H-pyrrolo[3,2-c]pyridineRelated Search:


  • 1-Boc-1H-pyrrolo[3,2-c]pyridine
  • 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 1,1-diMethylethyl ester
  • 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
  • 1-Boc-pyrrolo[3,2-c]pyridine, 95%
  • 148760-75-2