A 1120
- Product Name
- A 1120
- CAS No.
- 1152782-19-8
- Chemical Name
- A 1120
- Synonyms
- A 1120;A-1120,Inhibitor,inhibit,A 1120,A1120;2-(4-(2-(trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid;Benzoic acid, 2-[[[4-[2-(trifluoromethyl)phenyl]-1-piperidinyl]carbonyl]amino]-
- CBNumber
- CB82535656
- Molecular Formula
- C20H19F3N2O3
- Formula Weight
- 392.37
- MOL File
- 1152782-19-8.mol
A 1120 Property
- Boiling point:
- 572.3±50.0 °C(Predicted)
- Density
- 1.370±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: 100 mM; Ethanol: 25 mM
- form
- powder
- pka
- 4.03±0.36(Predicted)
- color
- off-white
Safety
- Hazard Codes
- Xn,N
- Risk Statements
- 22-36-43-50/53
- Safety Statements
- 26-36/37-60-61
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H400Very toxic to aquatic life
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A3111
- Product name
- A1120
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- A3111
- Product name
- A1120
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $563
- Updated
- 2024/03/01
- Product number
- 3793
- Product name
- A1120
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $186
- Updated
- 2021/12/16
- Product number
- 3793
- Product name
- A1120
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $785
- Updated
- 2021/12/16
- Product number
- A965350
- Product name
- A1120
- Packaging
- 2.5mg
- Price
- $220
- Updated
- 2021/12/16
A 1120 Chemical Properties,Usage,Production
Uses
A 1120 is a a nonretinoid RBP4 antagonist, which inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.
Biochem/physiol Actions
A1120 is a selective non-retinoid ligand for retinol-binding protein 4 (RBP4). RBP4 transports retinol from the liver to extrahepatic tissues and RBP4 lowering is reported to improve insulin sensitivity in mice. A1120 is a high affinity non-retinoid ligand for RBP4 which disrupts the interaction between RBP4 and its binding partner transthyretin (TTR). It binds to the same site as retinol and induces changes in the orientation (compared to the retinol bound form) of loops at the RBP4-TTR interaction interface.A1120 lowers RBP4 and retinol levels in a dose-dependent manner, to a similar extent as seen with fenretinide. However, unlike fenretinide (Sigma# H7779), A1120 does not have beneficial effects on insulin resistance.
storage
Store at RT
A 1120 Preparation Products And Raw materials
Raw materials
Preparation Products
A 1120 Suppliers
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4863
- Advantage
- 58
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8449
- Advantage
- 60
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
- Tel
- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57511
- Advantage
- 58
View Lastest Price from A 1120 manufacturers
- Product
- A 1120 1152782-19-8
- Price
- US $0.80-1.80/KG
- Min. Order
- 1KG
- Purity
- 95%~99.99%
- Supply Ability
- 10 MT/ Month
- Release date
- 2020-11-04