ChemicalBook > CAS DataBase List > Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE
Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE
- Product Name
- Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE
- CAS No.
- 114014-15-2
- Chemical Name
- Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE
- Synonyms
- Z-FY(T-BU)-DMK;Z-Phe-Tyr(tBu)-CHN2;Cbz-Phe-Tyr(O-t-Bu)-CHN2;CATHEPSIN L INHIBITOR III;Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE;CBZ-PHE-TYR(O-T-BU)-CHN2;Z-PHE-TYR(TBU)-CHN2
- CBNumber
- CB8254517
- Molecular Formula
- C31H34N4O5
- Formula Weight
- 542.63
- MOL File
- Mol file
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Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Property
- storage temp.
- -15°C
- solubility
- Ethyl Acetate: 10 mg/ml
- form
- A crystalline solid
- color
- White to off-white
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 219427
- Product name
- Cathepsin L Inhibitor III
- Purity
- The Cathepsin L Inhibitor III controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
- Packaging
- 5MG
- Price
- $202
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 27877
- Product name
- Z-Phe-Tyr(tBu)-diazomethylketone
- Packaging
- 1mg
- Price
- $38
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27877
- Product name
- Z-Phe-Tyr(tBu)-diazomethylketone
- Packaging
- 25mg
- Price
- $593
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27877
- Product name
- Z-Phe-Tyr(tBu)-diazomethylketone
- Packaging
- 5mg
- Price
- $139
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27877
- Product name
- Z-Phe-Tyr(tBu)-diazomethylketone
- Packaging
- 10mg
- Price
- $257
- Updated
- 2024/03/01
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Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Chemical Properties,Usage,Production
Uses
Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection[1][2].
Biological Activity
Cell permeable: yes', 'Primary Target
Cathepsin L', 'Product does not compete with ATP.', 'Reversible: no
IC 50
cathepsin L
References
[1] Ebert DH, et al. Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells. J Biol Chem. 2002 Jul 5;277(27):24609-17. DOI:10.1074/jbc.M201107200
[2] Perez-Bermejo JA, et al. SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19. Sci Transl Med. 2021 Apr 21;13(590):eabf7872. DOI:10.1126/scitranslmed.abf7872
Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Preparation Products And Raw materials
Raw materials
Preparation Products
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Z-PHE-TYR(TBU)-DIAZOMETHYLKETONE Suppliers
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