ChemicalBook > CAS DataBase List > PTEROIC ACID
PTEROIC ACID
- Product Name
- PTEROIC ACID
- CAS No.
- 119-24-4
- Chemical Name
- PTEROIC ACID
- Synonyms
- 4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid;Pyrofolic acid;4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid;NSC 14972;PTEROIC ACID;Butterfly acid;Pteroic Acid (>Pteroic acid >=93%;Pteroic Acid (>85%);Folic acid iMpurity D
- CBNumber
- CB8254618
- Molecular Formula
- C14H12N6O3
- Formula Weight
- 312.28
- MOL File
- 119-24-4.mol
More
Less
PTEROIC ACID Property
- Melting point:
- >400℃
- Boiling point:
- 610.0±65.0 °C(Predicted)
- Density
- 1.69
- storage temp.
- 2-8°C
- solubility
- Aqueous Base (Slightly), DMSO (Slightly)
- form
- powder
- pka
- 4.65±0.10(Predicted)
- color
- Light Yellow to Brown
More
Less
Safety
- WGK Germany
- 3
- HS Code
- 2933599590
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P1781
- Product name
- Pteroic acid
- Purity
- ≥93%
- Packaging
- 25mg
- Price
- $81.7
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P1781
- Product name
- Pteroic acid
- Purity
- ≥93%
- Packaging
- 50mg
- Price
- $131
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- PHR2002
- Product name
- Folic Acid Impurity D
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 100mg
- Price
- $647
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- Y0001243
- Product name
- Folic acid impurity D
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0001243
- Price
- $220
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P1781
- Product name
- Pteroic acid
- Purity
- ≥93%
- Packaging
- 100mg
- Price
- $255
- Updated
- 2024/03/01
More
Less
PTEROIC ACID Chemical Properties,Usage,Production
Uses
Pteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.
Uses
Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.
Definition
ChEBI: 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid is a pteroic acid. It is functionally related to a 2-aminopteridin-4-ol. It is a conjugate base of a 2-amino-6-{[(4-carboxyphenyl)amino]methyl}-4-hydroxypteridin-1-ium. It is a conjugate acid of a 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoate. It is a tautomer of a 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoic acid and a 4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoic acid.
General Description
Folic Acid Impurity D is an impurity of the water-soluble B-vitamin, folic acid. Folic Acid is generally used in the treatment of certain types of anemia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Enzyme inhibitor
This metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.
Purification Methods
Crystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]
PTEROIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
PTEROIC ACID Suppliers
- Tel
- 18915922978 18915922978
- 497743262@qq.com
- Country
- China
- ProdList
- 1011
- Advantage
- 58
- Tel
- 13961298435
- zzyqqq@163.com
- Country
- China
- ProdList
- 47
- Advantage
- 58
- Tel
- 18762678737
- 751546636@qq.com
- Country
- China
- ProdList
- 38
- Advantage
- 58
- Tel
- 0556-5032306 18917961636
- Fax
- +86-556-5032307
- wtx@bayeebio.com
- Country
- China
- ProdList
- 264
- Advantage
- 61
- Tel
- 15051477682
- changming.pan@csynbio.com
- Country
- China
- ProdList
- 246
- Advantage
- 58
- Tel
- 027-84492310 13657243668
- Fax
- 027-84492310
- wangting@vanzpharm.com
- Country
- China
- ProdList
- 50
- Advantage
- 58
- Tel
- 15051477682 15051477682
- 3833346036@qq.com
- Country
- China
- ProdList
- 163
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44689
- Advantage
- 61
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9510
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14103
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11655
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 020-13556033878 2965585218 13556033878
- Fax
- 0086-0757-85406358
- chemcell@hotmail.com
- Country
- China
- ProdList
- 369
- Advantage
- 52
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18738
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Country
- China
- ProdList
- 4554
- Advantage
- 62
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4001
- Advantage
- 55
- Tel
- 027-59207852 13308628970
- Fax
- QQ3130921841
- buy@fortunachem.com
- Country
- China
- ProdList
- 2859
- Advantage
- 58
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 0755-4000505016 13380397412
- Fax
- 0755 28094224
- 3001272453@qq.com
- Country
- China
- ProdList
- 5047
- Advantage
- 50
- Tel
- 0755-83725681-603
- Fax
- +86 755 28094224
- Country
- China
- ProdList
- 4496
- Advantage
- 50
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10266
- Advantage
- 58
- Tel
- 400-6206333 18021050169
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 020-39119399 18927568969
- Fax
- 020-39119999
- isunpharm@qq.com
- Country
- China
- ProdList
- 4674
- Advantage
- 55
- Tel
- 025-57798810
- Fax
- 025-57019371
- sales@sunlidabio.com
- Country
- China
- ProdList
- 3239
- Advantage
- 55
- Tel
- 021-021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7783
- Advantage
- 58
- Tel
- 0086-571-86217390
- Fax
- 0086-571-86217391
- Sales@gihichem.com
- Country
- China
- ProdList
- 860
- Advantage
- 58
- Tel
- 022-65378550-8551
- Fax
- +86-022-2532-9655
- contact@altascientific.com
- Country
- China
- ProdList
- 2773
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3991
- Advantage
- 60
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 18097
- Advantage
- 56
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9648
- Advantage
- 58
- Tel
- 400-8592883 15367835770
- Fax
- 0731-82251112
- viola@huatengsci.com
- Country
- China
- ProdList
- 5873
- Advantage
- 58
- Tel
- 0531-68652053
- 2310993908@qq.com
- Country
- China
- ProdList
- 1556
- Advantage
- 58
- Tel
- 15221275939 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 16166
- Advantage
- 55
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 13621943973
- Fax
- -
- sales@shjiyipharmatech.com
- Country
- China
- ProdList
- 1166
- Advantage
- 55
- Tel
- +86 (21) 61124340
- Fax
- +86 (21) 6129-4103
- Country
- China
- ProdList
- 9756
- Advantage
- 58
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51456
- Advantage
- 80
- Tel
- 18068075658
- Fax
- -
- sales@chempioneer.com
- Country
- China
- ProdList
- 1811
- Advantage
- 58
- Tel
- 18607101326 15172504745
- Fax
- +86-27-84254680
- aileen@chemfaces.com
- Country
- China
- ProdList
- 6905
- Advantage
- 55
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7888
- Advantage
- 55
- Tel
- 027-65388397 18164111589
- Fax
- 027-65388397
- 3321478047@qq.com
- Country
- China
- ProdList
- 1992
- Advantage
- 55
- Tel
- 021-54285032 13641685631
- Fax
- +86 (21) 5443 7651
- gerry.shu@hanjingchemicals.com
- Country
- China
- ProdList
- 76
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 27313
- Advantage
- 60
More
Less
View Lastest Price from PTEROIC ACID manufacturers
Wuhan Demeikai Biotechnology Co., Ltd
- Product
- Pteroic Acid 119-24-4
- Price
- US $10.00/g/Bag
- Min. Order
- 10g
- Purity
- 99
- Supply Ability
- 100KG
- Release date
- 2021-11-16
Hebei Minshang Biological Technology Co. LTD
- Product
- Pteroic Acid 119-24-4
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000t
- Release date
- 2021-05-07
Career Henan Chemical Co
- Product
- PTEROIC ACID 119-24-4
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-15
119-24-4, PTEROIC ACIDRelated Search:
(2S)-2-[[4-[Bis[(2-aMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoyl]aMino]pentanedioic Acid
2-Amino-7-(chloromethyl)pteridin-4(1H)-one
2-Amino-4-hydroxy-1H-pteridine
Erinacine A
Erinacin A
5-formyl-5,6,7,8-tetrahydropteroic acid
2-Amino-6-(chloromethyl)-4(3H)-pteridinone
Folitixorin (Mixture of DiastereoMers)
N-(4-aminobenzoyl)- D-Glutamic acid
Folic acid
5-Methyl Tetrahedropteroic Acid
(Mixture of DiastereoMers)
Folic Acid Impurity C
N-(p-Aminobenzoyl)glutamic acid
folic acid
5-Methyltetrahydrofolic acid
10-Formylfolic Acid
Folinic acid
6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE
L-Tetrahydrofolic Acid