1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product Name: 1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS No.: 847818-71-7
Chemical Name: 1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Synonyms: Pinacol 1-(2-methoxyethyl)-4-pyrazolyl-boronate;1-(2-Methoxyethyl)pyrazole-4-boronic Acid Pinacol Ester;1-(Methoxyethyl)-1H-pyrazole-4-boronic acid pinacol ester;1-(2-Methoxyethyl)-1H-pyrazole-4-boronic acid, pinacol ester;1-(2-METHOXYETHYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-;(1-(2-METHOXYETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER;1-(2-methoxyethyl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-(2-Methoxyethyl)-1H-pyrazole-4-boronic acid pinacol ester - [M15194];1-(2-METHOXYETHYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRAZOLE;1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CBNumber: CB82549839
Molecular Formula: C12H21BN2O3
Formula Weight: 252.12
MOL File: 847818-71-7.mol

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1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Property

Melting point:: 54 °C
Boiling point:: 356.4±22.0 °C(Predicted)
Density: 1.07±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: powder to crystal
pka: 1.87±0.10(Predicted)
color: White to Orange to Green

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Safety

HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3232
Product name: 1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Packaging: 200MG
Price: $50
Updated: 2025/07/31

TCI Chemical

Product number: M3232
Product name: 1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Packaging: 1G
Price: $150
Updated: 2025/07/31

TRC

Product number: M304368
Product name: 1-(2-Methoxyethyl)-1H-pyrazole-4-boronicacid,pinacolester
Packaging: 50mg
Price: $55
Updated: 2021/12/16

Chem-Impex

Product number: 39913
Product name: 1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole,98%(GC)
Purity: 98%(GC)
Packaging: 200MG
Price: $60.48
Updated: 2021/12/16

ChemScene

Product number: CS-W006072
Product name: 1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Packaging: 1g
Price: $86
Updated: 2021/12/16

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1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Chemical Properties,Usage,Production

Synthesis

269410-08-4

6482-24-2

847818-71-7

The reaction was carried out with 4-pyrazoleboronic acid pinacol ester (1.94 g, 10 mmol) and 2-bromoethyl methyl ether (1.68 g, 12 mmol) in a microwave reactor with stirring at 160 °C for 1 hour. Potassium carbonate (2.76 g, 20 mmol) and N,N-dimethylformamide (16 mL) were added as solvents to the reaction system. After completion of the reaction, the reaction mixture was concentrated and purified by silica gel column chromatography (eluent: 30% ethyl acetate/petroleum ether) to afford 1-(2-methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (2.2 g, 90% yield) as a yellow oil. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.32 (12H, s), 3.32 (3H, s), 3.75 (2H, t, J = 5.2 Hz), 4.30 (2H, t, J = 5.2 Hz), 7.77 (1H, s), 7.79 (1H, s). Mass spectral analysis: [M + H]+ m/z calculated value 253.2, measured value 253.2.

References

[1] Patent: WO2014/151106, 2014, A1. Location in patent: Paragraph 00179
[2] Patent: WO2011/51342, 2011, A1. Location in patent: Page/Page column 95
[3] Patent: US2011/269752, 2011, A1. Location in patent: Page/Page column 42
[4] Patent: WO2017/178416, 2017, A1. Location in patent: Page/Page column 115
[5] Patent: WO2014/37751, 2014, A1. Location in patent: Paragraph 00416-00418

1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Suppliers

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847818-71-7, 1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleRelated Search:

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1-(2-Methoxyethyl)-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 2-[1-(2-Methoxyethyl)-1H-pyrazol-4-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

1-(2-Methoxyethyl)-1H-pyrazole-4-boronic acid, pinacol ester

1-(2-Methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, Methyl 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethyl ether

Pinacol 1-(2-methoxyethyl)-4-pyrazolyl-boronate

1-(2-METHOXYETHYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRAZOLE

(1-(2-METHOXYETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER

1-(2-methoxyethyl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

1H-Pyrazole, 1-(2-methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

2-[1-(2-Methoxyethyl)-1H-pyrazol-4-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

1-(2-Methoxyethyl)pyrazole-4-boronic Acid Pinacol Ester

1-(2-METHOXYETHYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-

1-(2-Methoxyethyl)-1H-pyrazole-4-boronic acid pinacol ester - [M15194]

1-(Methoxyethyl)-1H-pyrazole-4-boronic acid pinacol ester

847818-71-7

C12H21BN2O3