(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride

Product Name: (R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride
CAS No.: 1204818-19-8
Chemical Name: (R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride
Synonyms: Sitagliptin-2;Sitalettinic acid;Sitagliptin Impurity 17;Sitagliptin Impurity 2 HCl;Sitagliptin Impurity 4 HCl;Sitagliptin Impurity 13 HCl;Sitagliptin Impurity 25 HCl;Sitagliptin Acid (USP IMP A);Sitagliptin Acid Impurity HCl;Sitagliptin FP Impurity E Hydrochloride
CBNumber: CB82550778
Molecular Formula: C10H11ClF3NO2
Formula Weight: 269.6480496
MOL File: 1204818-19-8.mol

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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Property

Melting point:: 218-220℃
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Sensitive: Air Sensitive
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: A630750
Product name: (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicAcidHydrochloride
Packaging: 250mg
Price: $145
Updated: 2021/12/16

AK Scientific

Product number: B604
Product name: (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacidhydrochloride
Packaging: 25mg
Price: $49
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0010959
Product name: (R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $501.28
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0010959
Product name: (R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE
Purity: 95.00%
Packaging: 250MG
Price: $776
Updated: 2021/12/16

Alichem

Product number: 1204818198
Product name: (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacidhydrochloride
Packaging: 5g
Price: $795.96
Updated: 2021/12/16

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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Chemical Properties,Usage,Production

Uses

(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride is an intermediate in the synthesis of the new antidiabetic drug Sitagliptine (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor.

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Suppliers

China 65 India 6 United States 4 Global 75

Adamas Reagent, Ltd.

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Email: info@hanhongsci.com
Country: China
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Country: China
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SINO High Goal Chemical Technology Co., Ltd.

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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1204818-19-8, (R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochlorideRelated Search:

Sitagliptin Impurity 28 Sitagliptin Impurity 46 Sitagliptin Impurity 77 Sitagliptin impurity 5 Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Sitagliptin Impurity 34 2,4,5-TRIFLUOROBENZYL CHLORIDE (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin Sitagliptin Impurity 14 Sitagliptin Defuoro IMpurity 5 Sitagliptin DeaMino IMpurity 1 (S)-Sitagliptin Phosphate 2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

(R)-b-Amino-2,4,5-trifluoro-benzenebutanoic acid HCl

Sitagliptin Impurity 17

Sitagliptin Acid Impurity HCl

Sitagliptin-2

Sitagliptin impurity 37/(R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid hydrochloride

(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride

(R)-3-amino-4-phenyl(2,4,5-trifluorophenyl)butanoic acid hydrochloride

(3R)-3-amino -4-(2, 4-difluorophenyl)-1-[3-(trifluoromethyl)butyl]-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]butan-1-one

Sitagliptin FP Impurity E Hydrochloride

(R)-b-Amino-2,4,5-trifluoro-benzenebutanoic acid hydrochloride

Sitagliptin Impurity 25 HCl

Sitalettinic acid

Sitagliptin Acid (USP IMP A)

(βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride

Sitagliptin Impurity 2 HCl

Sitagliptin Impurity 13 HCl

Sitagliptin Impurity 4 HCl

Sitagliptin FP Impurity E (Sitagliptin Phosphate Monohydrate Acid Impurity)

1204818-19-8