ChemicalBook > CAS DataBase List > (R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride

Product Name
(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride
CAS No.
1204818-19-8
Chemical Name
(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride
Synonyms
Sitagliptin-2;Sitalettinic acid;Sitagliptin Impurity 17;Sitagliptin Impurity 2 HCl;Sitagliptin Impurity 4 HCl;Sitagliptin Impurity 13 HCl;Sitagliptin Impurity 25 HCl;Sitagliptin Acid (USP IMP A);Sitagliptin Acid Impurity HCl;Sitagliptin FP Impurity E Hydrochloride
CBNumber
CB82550778
Molecular Formula
C10H11ClF3NO2
Formula Weight
269.6480496
MOL File
1204818-19-8.mol
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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Property

Melting point:
218-220℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Sensitive 
Air Sensitive
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
A630750
Product name
(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicAcidHydrochloride
Packaging
250mg
Price
$145
Updated
2021/12/16
AK Scientific
Product number
B604
Product name
(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacidhydrochloride
Packaging
25mg
Price
$49
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0010959
Product name
(R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$501.28
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0010959
Product name
(R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID HYDROCHLORIDE
Purity
95.00%
Packaging
250MG
Price
$776
Updated
2021/12/16
Alichem
Product number
1204818198
Product name
(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacidhydrochloride
Packaging
5g
Price
$795.96
Updated
2021/12/16
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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Chemical Properties,Usage,Production

Uses

(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride is an intermediate in the synthesis of the new antidiabetic drug Sitagliptine (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor.

(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride Suppliers

China 60 India 5 United States 4 Global 69
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
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Shanghai Feibo Chemical Technology Co., Ltd
Tel
021-58955608,2250286 15921236618
Email
blinkzeng@gmail.com
Country
China
ProdList
523
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62
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
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han_yajun@dctc.daicel.com
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China
ProdList
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4972
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Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-52878169 15701683040
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sales@bjcomparison.com
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China
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4689
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58
SINO High Goal Chemical Technology Co., Ltd.
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021-57646680 18306277365
Fax
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China
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Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
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China
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
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1204818-19-8, (R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochlorideRelated Search:

Sitagliptin Impurity 28 Sitagliptin Impurity 46 Sitagliptin Impurity 77 Sitagliptin impurity 5 Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Sitagliptin Impurity 34 2,4,5-TRIFLUOROBENZYL CHLORIDE (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin Sitagliptin Impurity 14 Sitagliptin Defuoro IMpurity 5 Sitagliptin DeaMino IMpurity 1 (S)-Sitagliptin Phosphate 2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

  • (R)-b-Amino-2,4,5-trifluoro-benzenebutanoic acid HCl
  • Sitagliptin Impurity 17
  • Sitagliptin Acid Impurity HCl
  • Sitagliptin-2
  • Sitagliptin impurity 37/(R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid hydrochloride
  • (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride
  • (R)-3-amino-4-phenyl(2,4,5-trifluorophenyl)butanoic acid hydrochloride
  • (3R)-3-amino -4-(2, 4-difluorophenyl)-1-[3-(trifluoromethyl)butyl]-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]butan-1-one
  • Sitagliptin FP Impurity E Hydrochloride
  • (R)-b-Amino-2,4,5-trifluoro-benzenebutanoic acid hydrochloride
  • Sitagliptin Impurity 25 HCl
  • Sitalettinic acid
  • Sitagliptin Acid (USP IMP A)
  • (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride
  • Sitagliptin Impurity 2 HCl
  • Sitagliptin Impurity 13 HCl
  • Sitagliptin Impurity 4 HCl
  • Sitagliptin FP Impurity E (Sitagliptin Phosphate Monohydrate Acid Impurity)
  • 1204818-19-8