2-chloroethanesulfonyl chloride

Product Name: 2-chloroethanesulfonyl chloride
CAS No.: 1622-32-8
Chemical Name: 2-chloroethanesulfonyl chloride
Synonyms: oroethanesuL;2-chloroethanesulfochloride;2-chloroethylsulfonylchloride;2-chloro-ethanesulfonylchlorid;2-CHLOROETHANESULFONYL CHLORIDE;2-chloroethanesulfochloride[qr];2-CHLOROETHANESULPHONYL CHLORIDE;(2-chloroethyl)sulphonyl chloride;beta-chloroethanesulfonylchloride;2-chloroethylsulfonylchloride[qr]
CBNumber: CB8257215
Molecular Formula: C2H4Cl2O2S
Formula Weight: 163.02
MOL File: 1622-32-8.mol

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2-chloroethanesulfonyl chloride Property

Melting point:: 3 °C
Boiling point:: 84-86 °C15 mm Hg(lit.)
Density: 1.56 g/mL at 25 °C(lit.)
vapor pressure: 15 mm Hg ( 84 °C)
refractive index: n20/D 1.493(lit.)
Flash point:: >230 °F
storage temp.: Refrigerator
form: Liquid
color: Clear slightly yellow to brown
Water Solubility: Reacts with water.
Sensitive: Moisture Sensitive
BRN: 1751202
InChI: InChI=1S/C2H4Cl2O2S/c3-1-2-7(4,5)6/h1-2H2
InChIKey: VHCSBTPOPKFYIU-UHFFFAOYSA-N
SMILES: C(S(Cl)(=O)=O)CCl
CAS DataBase Reference: 1622-32-8(CAS DataBase Reference)
EPA Substance Registry System: 2-Chloro-ethanesulfonyl chloride (1622-32-8)

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Safety

Hazard Codes: T+
Risk Statements: 22-26-34-36
Safety Statements: 26-28-36/37/39-45-23
RIDADR: UN 3390 6.1/PG 1
WGK Germany: 3
RTECS: KI8060000
F: 10-19
TSCA: Y
HazardClass: 8
PackingGroup: II
HS Code: 29049090
Hazardous Substances Data: 1622-32-8(Hazardous Substances Data)
Toxicity: mouse,LC50,inhalation,250mg/m3/4H (250mg/m3),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(6), Pg. 59, 1971.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

H330Fatal if inhaled

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 302325
Product name: 2-Chloroethanesulfonyl chloride
Purity: 96%
Packaging: 5g
Price: $45.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 302325
Product name: 2-Chloroethanesulfonyl chloride
Purity: 96%
Packaging: 25g
Price: $112
Updated: 2024/03/01

TCI Chemical

Product number: C1142
Product name: 2-Chloroethanesulfonyl Chloride
Purity: >95.0%(GC)(T)
Packaging: 25g
Price: $52
Updated: 2024/03/01

TCI Chemical

Product number: C1142
Product name: 2-Chloroethanesulfonyl Chloride
Purity: >95.0%(GC)(T)
Packaging: 100g
Price: $171
Updated: 2024/03/01

Alfa Aesar

Product number: A15377
Product name: 2-Chloroethanesulfonyl chloride, 98%
Packaging: 10g
Price: $54.4
Updated: 2024/03/01

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2-chloroethanesulfonyl chloride Chemical Properties,Usage,Production

Chemical Properties

CLEAR SLIGHTLY YELLOW TO BROWN LIQUID

Uses

2-Chloroethanesulfonyl chloride was used in one-pot sulfonylation/intramolecular thia-Michael protocol for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. It was also used in synthesis of vinyl sulfonamides with a furan, carbocyclic, semi cyclic or acyclic 1,3-diene moiety.

Application

As a precursor of the bis-electrophilic synthon vinylsulfonyl chloride, 2-chloroethanesulfonyl chloride can react with a wide range of bis-nucleophilic synthons, such as substituted 2-amino alcohols, to generate 7-membered sultams. This compound can be used in lieu of vinylsulfonyl chloride via a domino elimination– amidation reaction[1-2].

General Description

A liquid. Density 1.56 g / cm3. Flash point exceeds 230°F.

Air & Water Reactions

Reacts with water to produce corrosive and toxic gaseous hydrogen chloride.

Reactivity Profile

2-CHLOROETHANESULFONYL CHLORIDE is incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

References

[1] Qin Zang. “Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-Pot Sulfonylation/Thia-Michael Protocol.” Heterocycles 86 2 (2012).
[2] Victor O Rogachev, Peter Metz. “Thermal and high pressure intramolecular Diels–Alder reaction of vinylsulfonamides.” Nature Protocols 1 6 (2007): 3076–3087.

2-chloroethanesulfonyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-chloroethanesulfonyl chloride Suppliers

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View Lastest Price from 2-chloroethanesulfonyl chloride manufacturers

Hubei Lidu New Material Technology Co., Ltd

Product: 2-CHLOROETHANESULFONYL CHLORIDE 1622-32-8
Price: US $0.00/kg
Min. Order: 10kg
Purity: 97%
Supply Ability: 20tons
Release date: 2024-09-23

Career Henan Chemical Co

Product: 2-CHLOROETHANESULFONYL CHLORIDE 1622-32-8
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

1622-32-8, 2-chloroethanesulfonyl chlorideRelated Search:

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beta-chloroethanesulfonylchloride

beta-chloroethanesulfonylchloride[qr]

ethanesulfonylchloride,2-chloro-[qr]

(2-chloroethyl)sulphonyl chloride

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2-Chloroethanesulfonoic acid chlorohydride

oroethanesuL

2-chloroethanesulfochloride

2-chloroethanesulfochloride[qr]

2-chloro-ethanesulfonylchlorid

2-chloroethanesulfonylchloride[qr]

2-chloroethylsulfonylchloride

2-chloroethylsulfonylchloride[qr]

2-Chloroethanesulfonyl Chloride &gt

Ethanesulfonyl chloride, 2-chloro-

1622-32-8

C2H4S2O2Cl2

C2H4O2Cl2S

ClCH2CH2SO2Cl

C2H4Cl2O2S

SULFONYL CHLORIDE

Sulfonyl Halides

Synthetic Reagents

Sulfur Compounds

Others

Sulfur Compounds (for Synthesis)

Building Blocks

Protecting and Derivatizing Reagents

Protection and Derivatization

Organic Building Blocks

Sulfur Compounds (for Synthesis)

Synthetic Organic Chemistry

Others

Organic Building Blocks

Sulfonyl Halides

Sulfur Compounds

Protecting and Derivatizing Reagents

Protection and Derivatization