5-ethynyl-2-pyridinaMine
- Product Name
- 5-ethynyl-2-pyridinaMine
- CAS No.
- 82454-61-3
- Chemical Name
- 5-ethynyl-2-pyridinaMine
- Synonyms
- 5-ethynyl-2-pyridinaMine;5-Ethynylpyridin-2-aMine;2-aMino-5-ethynylpyridine;2-Pyridinamine, 5-ethynyl-;5-Ethynyl-pyridin-2-ylamine
- CBNumber
- CB82616520
- Molecular Formula
- C7H6N2
- Formula Weight
- 118.14
- MOL File
- 82454-61-3.mol
5-ethynyl-2-pyridinaMine Property
- Melting point:
- 127-129 °C
- Boiling point:
- 246.5±25.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 5.13±0.13(Predicted)
- Appearance
- Yellow to orange Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H361Suspected of damaging fertility or the unborn child
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313IF exposed or concerned: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P391Collect spillage. Hazardous to the aquatic environment
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E13964
- Product name
- 5-Ethynylpyridin-2-amine
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- AS44280
- Product name
- 5-Ethynylpyridin-2-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $159
- Updated
- 2021/12/16
- Product number
- AS44280
- Product name
- 5-Ethynylpyridin-2-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $313
- Updated
- 2021/12/16
- Product number
- E13964
- Product name
- 5-Ethynylpyridin-2-amine
- Packaging
- 1g
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CHM0390732
- Product name
- 5-ETHYNYLPYRIDIN-2-AMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.31
- Updated
- 2021/12/16
5-ethynyl-2-pyridinaMine Chemical Properties,Usage,Production
Uses
5-Ethynyl-2-pyridinamine (CAS:82454-61-3) is a useful research compound.
Synthesis
457628-40-9
82454-61-3
General procedure for the synthesis of 5-alkynylpyridin-2-amines from 2-amino-5-[(trimethylsilyl)ethynyl]pyridines: To a mixed solution of 5-trimethylsilyl ethynyl-pyridin-2-ylamine (26 mg, 137 μmol) described in Preparation Example 28-1-2 in tetrahydrofuran (1 mL) and methanol (1 mL) was added potassium carbonate (37.9 mg, 274 μ mol). The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction solution was partitioned into water and ethyl acetate at 0 °C for extraction. The organic layer was washed with saturated aqueous sodium chloride solution and dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by silica gel column chromatography (eluent: heptane/ethyl acetate=1:1) to afford the target product 5-alkynylpyridin-2-amines (16 mg, 99% yield).1H-NMR (CDCl3) δ (ppm): 3.07 (1H, s), 4.73 (2H, brs), 6.46 (1H, d, J=8.6 Hz). 7.53 (1H, dd, J=2.2,8.6 Hz), 8.21 (1H, s).
References
[1] Patent: US2009/82403, 2009, A1. Location in patent: Page/Page column 76-77
[2] Patent: US2007/105904, 2007, A1. Location in patent: Page/Page column 74
[3] Dalton Transactions, 2006, vol. 6, # 13, p. 1627 - 1635
[4] Patent: WO2005/90333, 2005, A1. Location in patent: Page/Page column 71
[5] Patent: US2007/287739, 2007, A1. Location in patent: Page/Page column 7
5-ethynyl-2-pyridinaMine Preparation Products And Raw materials
Raw materials
Preparation Products
5-ethynyl-2-pyridinaMine Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 025-66028182 18626450290
- yftan@aikonchem.com
- Country
- China
- ProdList
- 16679
- Advantage
- 50
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 13675155016
- Fax
- 18912765016
- tongtf110@sina.com
- Country
- China
- ProdList
- 963
- Advantage
- 55
- Tel
- 0-2022843681 15618226720
- Fax
- +86-21-51601218
- chaolaichem@foxmail.com
- Country
- China
- ProdList
- 12476
- Advantage
- 58
View Lastest Price from 5-ethynyl-2-pyridinaMine manufacturers
- Product
- 5-ethynyl-2-pyridinaMine 82454-61-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12