1,2,4,5-Tetramethylbenzene

Product Name: 1,2,4,5-Tetramethylbenzene
CAS No.: 95-93-2
Chemical Name: 1,2,4,5-Tetramethylbenzene
Synonyms: DURENE;DUROL;1,2,4,5-TetramethyL;1,2,4,5-TERAMETHYLBENZENE;Durol[R];1.2.4.5-TetraM;Thymol Impurity?40;1,2,4,5-Tetramethylb;Durene 5g [95-93-2];2,5-dimethyl-p-xylen
CBNumber: CB8262899
Molecular Formula: C10H14
Formula Weight: 134.22
MOL File: 95-93-2.mol

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1,2,4,5-Tetramethylbenzene Property

Melting point:: 78 °C
Boiling point:: 196-197 °C
Density: 0.838 g/mL at 25 °C(lit.)
vapor density: 4.6 (vs air)
vapor pressure: 160 mm Hg ( 140 °C)
refractive index: 1.5093
Flash point:: 165 °F
storage temp.: Flammables area
solubility: 0.00348g/l
form: crystals
color: White to Almost white
Specific Gravity: 0.838
Odor: rancid sweet
Water Solubility: insoluble
Merck: 14,3468
BRN: 1903393
Henry's Law Constant: 2.49 at 25 °C (approximate - calculated from water solubility and vapor pressure)
InChI: 1S/C10H14/c1-7-5-9(3)10(4)6-8(7)2/h5-6H,1-4H3
InChIKey: SQNZJJAZBFDUTD-UHFFFAOYSA-N
SMILES: Cc1cc(C)c(C)cc1C
LogP: 4.000
CAS DataBase Reference: 95-93-2(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1,2,4,5-tetramethyl-(95-93-2)
EPA Substance Registry System: 1,2,4,5-Tetramethylbenzene (95-93-2)

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Safety

Hazard Codes: F,N
Risk Statements: 11-53-50
Safety Statements: 16-61
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 1
RTECS: DC0500000
TSCA: TSCA listed
HazardClass: 4.1
PackingGroup: III
HS Code: 29029080
Storage Class: 4.1B - Flammable solid hazardous materials
Hazard Classifications: Aquatic Acute 1
Aquatic Chronic 1
Flam. Sol. 1
Toxicity: LD50 orally in Rabbit: 6700 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T19607
Product name: 1,2,4,5-Tetramethylbenzene
Purity: 98%
Packaging: 100g
Price: $69.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: 74658
Product name: 1,2,4,5-Tetramethylbenzene
Purity: Standard for quantitative NMR, TraceCERT
Packaging: 1g
Price: $224
Updated: 2025/07/31

TCI Chemical

Product number: T0140
Product name: 1,2,4,5-Tetramethylbenzene Zone Refined (number of passes:23)
Purity: >99.8%(GC)
Packaging: 1sample
Price: $167
Updated: 2023/06/20

TCI Chemical

Product number: T0714
Product name: 1,2,4,5-Tetramethylbenzene
Purity: >98.0%(GC)
Packaging: 25g
Price: $40
Updated: 2025/07/31

Sigma-Aldrich

Product number: T19607
Product name: 1,2,4,5-Tetramethylbenzene
Purity: 98%
Packaging: 500g
Price: $141
Updated: 2025/07/31

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1,2,4,5-Tetramethylbenzene Chemical Properties,Usage,Production

Chemical Properties

white to brown semi-transparent crystals

Physical properties

Colorless crystals or scales with a camphor-like odor

Uses

Plasticizers; polymers; fibers; organic synthesis.

Uses

1,2,4,5-Tetramethylbenzene is used in method for reducing odor in room in remodeling work by removing causative substances.

Definition

ChEBI: Durene is a tetramethylbenzene carrying methyl groups at positions 1, 2, 4 and 5.

General Description

Colorless crystals with a camphor-like odor.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as 1,2,4,5-Tetramethylbenzene, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.

Synthesis

Even tetramethylbenzene is one of the components of coal tar, originally prepared from metatrimethylbenzene in 1870. It is obtained by the methylation reaction of other toluene, such as p-xylene or meta-trimethylbenzene.
C6H4(CH3)2 + 2CH3Cl → C6H2(CH3)4 + 2 HCl
Industrially produced using the alkylation reaction of xylene with trimethylbenzene and methanol. Homotetramethylene can be selectively crystallized from its isomers based on its high melting point. Primitive syntheses include similar reactions with toluene as a feedstock.

Purification Methods

Chromatograph durene on alumina, and recrystallise it from aqueous EtOH or *benzene. Zone-refining removes duroaldehydes. Dry it under vacuum. [Yamauchi et al. J Phys Chem 89 4804 1985.] It has also been sublimed in vacuo [Johnston et al. J Am Chem Soc 109 1291 1987]. [Beilstein 5 H 431, 5 I 207, 5 II 329, 5 III 979, 5 IV 1076.]

Toxics Screening Level

The initial threshold screening level (ITSL) for 1,2,4,5-tetramethyl benzene is 20 μg/m3 (annual averaging time).

1,2,4,5-Tetramethylbenzene Preparation Products And Raw materials

Raw materials

1,2,4-Trimethylbenzene Dark green m-Xylene Methanol Sodium hydroxide tetramethylbenzene Aluminium chloride hexahydrate Chloromethane

Preparation Products

2,3,5,6-TETRAMETHYLBENZALDEHYDE Pyromellitic Dianhydride Mesitylene Pyromellitic acid

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1,2,4,5-Tetramethylbenzene Suppliers

Belgium 3 CHINA 179 Europe 3 France 1 Germany 7 India 6 Japan 3 Norway 1 South Korea 1 Spain 1 Switzerland 2 Ukraine 1 United Kingdom 7 United States 30 Global 245

Beijing XinaoXunchi Chemical CO., LTD

Tel: 010-89340150 13651234369
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
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Alfa Aesar

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Energy Chemical

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Syntechem Co.,Ltd

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Sichuan Kulinan Technology Co., Ltd

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View Lastest Price from 1,2,4,5-Tetramethylbenzene manufacturers

Hebei Miaobian Biotechnology Co., Ltd

Product: 1,2,4,5-Tetramethylbenzene 95-93-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.99
Supply Ability: 10Ton
Release date: 2021-02-18

Career Henan Chemical Co

Product: 1,2,4,5-Tetramethylbenzene 95-93-2
Price: US $6.60/KG
Min. Order: 500g
Purity: 98%
Supply Ability: 1kg, 50kg, 100kg
Release date: 2019-12-25

95-93-2, 1,2,4,5-TetramethylbenzeneRelated Search:

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1,2,4,5-TETRAMETHYLBENZENE (DURENE)

1,2,4,5-Tetramethylbenzene, 97+%

1,2,4,5-Tetramethylbenzene Zone Refined (number of passes:23)

Durene,1,2,4,5-Tetramethylbenzene

Durene 5g [95-93-2]

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1,2,4,5-Tetramethylb

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Zone Refined (nuMber of passes:23)

1,2,4,5-TetraMethylbenzene, 99% 100GR

1,2,4,5-TetraMethylbenzene, 99% 500GR

1,2,4,5-Tetramethylbenzoate

2,5-Dimethyl-p-xylene

1,2,4,5-Tetramethylbenzene,98%

1,2,4,5-Tetramethylbenzene Zone Refined

1,2,4,5-TETRAMETHYLBENZENE FOR SYNTHESIS

1,2,4,5-Tetramethylbenzene (Durene) 10 μg/mL in Cyclohexane

benzene,1,2,4,5-tetramethyl-

I,i,4,5-Tetramcthylben~oiaG

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LABOTEST-BB LT00852111

DUROL

DURENE

1,2,4,5-Tetramethylbenzene,99%

Durol[R]

durene,1,2,4,5-tetramethylbenzene,durol

1,2,4,5-TERAMETHYLBENZENE

1,2,4,5-Tetramethylbenzol

1,2,4,5-Tetramethylbenzene Zone Refined (number of passes:23)&gt

1,2,4,5-Tetramethylbenzene &gt

1,2,4,5-TetramethylbenzeneSolution,1000mg/L

1,2,4,5-TetramethyL

99% purity 1,2,4,5-Tetramethylbenzene

Thymol Impurity?40

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C17412500 1,2,4,5-Tetramethylbenzene

L17412500CY 1,2,4,5-TetramethylbenzenE10μg/mL

95-93-2

1856-04-3

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