Boc-NH-PEG(5)-COOH(22atoMs)

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Boc-NH-PEG(5)-COOH(22atoMs)

Product Name: Boc-NH-PEG(5)-COOH(22atoMs)
CAS No.: 391684-36-9
Chemical Name: Boc-NH-PEG(5)-COOH(22atoMs)
Synonyms: Boc-NH-PEG(5)-COOH;NHBoc-PEG6-CH2COOH;Boc-NM-PEG6-CM2COOH;t-Boc-N-amido-PEG6-CH2CO2H;Boc-NH-PEG(5)-COOH(22atoMs);t-boc-N-amido-PEG6-acetic acid;2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-oic acid;5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(1,1-dimethylethyl) ester;Inhibitor,Boc-NH-PEG-6-CH2COOH,PROTAC Linkers,BocNHPEG6CH2COOH,Boc NH PEG6 CH2COOH,inhibit;2-(2-(2-(2-(2-(2-t-butyloxycarbonylaminoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxyacetatic acid
CBNumber: CB82648725
Molecular Formula: C19H37NO10
Formula Weight: 439.5
MOL File: 391684-36-9.mol

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Boc-NH-PEG(5)-COOH(22atoMs) Property

Boiling point:: 557.7±50.0 °C(Predicted)
Density: 1.134±0.06 g/cm3(Predicted)
storage temp.: -20°C
pka: 3.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 902675
Product name: BocNH-PEG6-acid
Packaging: 250mg
Price: $252
Updated: 2024/03/01

Sigma-Aldrich

Product number: 902675
Product name: BocNH-PEG6-acid
Packaging: 1g
Price: $775
Updated: 2024/03/01

BroadPharm

Product number: BP-24355
Product name: t-Boc-N-amido-PEG6-CH2CO2H
Purity: 98%
Packaging: 250mg
Price: $240
Updated: 2021/12/16

BroadPharm

Product number: BP-24355
Product name: t-Boc-N-amido-PEG6-CH2CO2H
Purity: 98%
Packaging: 1g
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-24355
Product name: t-Boc-N-amido-PEG6-CH2CO2H
Purity: 98%
Packaging: 500mg
Price: $380
Updated: 2021/12/16

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Boc-NH-PEG(5)-COOH(22atoMs) Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG6-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG₆-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^? molecules) for targeted protein degradation.

Boc-NH-PEG(5)-COOH(22atoMs) Preparation Products And Raw materials

Raw materials

Preparation Products

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391684-36-9, Boc-NH-PEG(5)-COOH(22atoMs)Related Search:

Boc-NH-PEG12-CH2CH2COOH BocNH-PEG8-CH2CH2NH2 BocNH-PEG11-OH BocNH-PEG12-CH2CH2NH2 t-Boc-N-amido-PEG5-acid O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) N-Boc-PEG5-alcohol N-Boc-PEG4-bromide

Boc-NH-PEG(5)-COOH(22atoMs)

Boc-NH-PEG(5)-COOH

Boc-NM-PEG6-CM2COOH

2-(2-(2-(2-(2-(2-t-butyloxycarbonylaminoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxyacetatic acid

t-Boc-N-amido-PEG6-CH2CO2H

t-boc-N-amido-PEG6-acetic acid

NHBoc-PEG6-CH2COOH

Inhibitor,Boc-NH-PEG-6-CH2COOH,PROTAC Linkers,BocNHPEG6CH2COOH,Boc NH PEG6 CH2COOH,inhibit

BocNH-PEG6-CH2COOH/5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(1,1-dimethylethyl) ester

5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(1,1-dimethylethyl) ester

2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-oic acid

2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-oic acid, Boc-NH-PEG6-CH2COOH

2-[2-[2-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

391684-36-9

C19H37NO10