Hederacolchiside A1
- Product Name
- Hederacolchiside A1
- CAS No.
- 106577-39-3
- Chemical Name
- Hederacolchiside A1
- Synonyms
- Raddeanoside R13;Hederacolchiside A1;HEDERACOLCHISIDE A1;;Black sea ivy glycoside A1;Hederacolchiside A1 USP/EP/BP;Hederacolchiside A1, 10 mM in DMSO;Oleanolic acid-3-O-β-D-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)--α-L-arabinopyranoside,Hederacolchiside A1;Oleanolic acid-3-O-β-D-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)-]-α-L-arabinopyranoside,Hederacolchiside A1;Olean-12-en-28-oicacid, 3-[(O-6-deoxy-a-L-mannopyranosyl-(12)-O-[b-D-glucopyranosyl-(14)]-a-L-arabinopyranosyl)oxy]-, (3b)-;Olean-12-en-28-oic acid, 3-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl)oxy]-, (3β)-
- CBNumber
- CB82654098
- Molecular Formula
- C47H76O16
- Formula Weight
- 897.1
- MOL File
- 106577-39-3.mol
Hederacolchiside A1 Property
- Melting point:
- 253-255℃ (methanol , water )
- Boiling point:
- 967.2±65.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- 4°C, protect from light
- solubility
- Soluble in DMSO
- pka
- 4?+-.0.70(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- PHL85876
- Product name
- Hederacolchiside A1
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $480
- Updated
- 2025/07/31
- Product number
- 300404
- Product name
- Hederacolchiside A1
- Packaging
- 5mg
- Price
- $915
- Updated
- 2021/12/16
- Product number
- orb259289
- Product name
- Hederacolchiside A1
- Purity
- 98%
- Packaging
- 5mg
- Price
- $1079.5
- Updated
- 2021/12/16
- Product number
- N2047
- Product name
- Hederacolchiside A1
- Packaging
- 5mg
- Price
- $800
- Updated
- 2021/12/16
- Product number
- CS-0027961
- Product name
- Hederacolchiside A1
- Purity
- 99.69%
- Packaging
- 5mg
- Price
- $202
- Updated
- 2021/12/16
Hederacolchiside A1 Chemical Properties,Usage,Production
Uses
Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway[1]. Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro[2].
in vivo
hederacolchiside A1 (3.0, 4.5, and 6.0?mg/kg, ip) can significantly inhibit the weight of tumor in an H22 xenograft model[1].
Hederacolchiside A1 (3.25, 7.5, and 15.0?mg/kg, ig) can significantly inhibit the weight of tumor in nude mice xenograft tumor models using human breast carcinoma MCF-7 cells[1].
IC 50
Schistosome; PI3K; mTOR
References
[1] Yan-Er Wang, et al. Hederacolchiside A1 suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. Chinese Herbal Medicines.Volume 10, Issue 2, April 2018, Pages 215-222
[2] Kang N, et al. Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis. Molecules. 2018 Jun 13;23(6). DOI:10.3390/molecules23061431
Hederacolchiside A1 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hederacolchiside A1 manufacturers
- Product
- Hederacolchiside A1 106577-39-3
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-21
- Product
- Hederacolchiside A1 106577-39-3
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- >98%HPLC
- Supply Ability
- 20 tons
- Release date
- 2020-02-06