spiro<3.3>heptane-3-carboxylic acid
Uses- Product Name
- spiro<3.3>heptane-3-carboxylic acid
- CAS No.
- 28114-87-6
- Chemical Name
- spiro<3.3>heptane-3-carboxylic acid
- Synonyms
- 3.3>spiro<heptane-3-carboxylic acid;spiro<3.3>heptane-3-carboxylic acid;Spiro[3.3]heptane-2-carboxylic acid - S11733;Spiro[3.3]heptane-2-carboxylic acid (7CI, 8CI, 9CI, ACI)
- CBNumber
- CB82655343
- Molecular Formula
- C8H12O2
- Formula Weight
- 140.18
- MOL File
- 28114-87-6.mol
spiro<3.3>heptane-3-carboxylic acid Property
- Melting point:
- 25 °C
- Boiling point:
- 256.8±8.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- liquid
- pka
- 4.77±0.20(Predicted)
- color
- Colourless
- InChI
- InChI=1S/C8H12O2/c9-7(10)6-4-8(5-6)2-1-3-8/h6H,1-5H2,(H,9,10)
- InChIKey
- FUQHLUSGMOSPRQ-UHFFFAOYSA-N
- SMILES
- C1C2(CCC2)CC1C(O)=O
Safety
- HS Code
- 2916200090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- S682525
- Product name
- Spiro[3.3]heptane-2-carboxylicacid
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CHM1052105
- Product name
- SPIRO[3.3]HEPTANE-2-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $452.05
- Updated
- 2021/12/16
- Product number
- 2221-1-28
- Product name
- Spiro[3.3]heptane-2-carboxylic acid
- Packaging
- 1g
- Price
- $525
- Updated
- 2021/12/16
- Product number
- 113256
- Product name
- Spiro[3.3]heptane-2-carboxylic acid
- Packaging
- 1g
- Price
- $851
- Updated
- 2021/12/16
- Product number
- 4504AJ
- Product name
- Spiro[3.3]heptane-2-carboxylicacid
- Packaging
- 5g
- Price
- $1451
- Updated
- 2021/12/16
spiro<3.3>heptane-3-carboxylic acid Chemical Properties,Usage,Production
Uses
Spiro[3.3]heptane-2-carboxylic acid is a carboxylic acid derivative that can be used as a pharmaceutical intermediate.
Synthesis
64775-97-9
28114-87-6
The general procedure for the synthesis of spiro[3.3]heptane-2,2-dicarboxylic acid from spiro[3.3]heptane-2,2-dicarboxylic acid was as follows: spiro[3.3]heptane-2,2-dicarboxylic acid (1.737 g, 9.43 mmol) was dissolved in pyridine (20 mL) and the reaction was heated at 115 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated to dryness in a rotary evaporator. The resulting residue was treated with 6 M aqueous hydrochloric acid and subsequently extracted with dichloromethane (3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated to dryness to afford spiro[3.3]heptane-2-carboxylic acid (1.21 g, 92% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 11.98 (s, 1H), 2.85 (m, 1H), 2.15-2.03 (m, 4H), 1.96 (t, J = 7.3 Hz, 2H), 1.84 (t, J = 7.3 Hz, 2H), 1.76-1.70 (m, 2H).
References
[1] Patent: US2014/275080, 2014, A1. Location in patent: Paragraph 0368
[2] Justus Liebigs Annalen der Chemie, 1961, vol. 648, p. 36 - 50
spiro<3.3>heptane-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
spiro<3.3>heptane-3-carboxylic acid Suppliers
- Tel
- 13356901049
- mark@sklnchem.cn
- Country
- China
- ProdList
- 7999
- Advantage
- 58
- Tel
- 021-50929289 18616309303
- Fax
- -
- sales@ypptech.com.cn
- Country
- China
- ProdList
- 287
- Advantage
- 58
- Tel
- 13752273685
- 40472474@qq.com
- Country
- China
- ProdList
- 117
- Advantage
- 58
- Tel
- 021-57171705 13817537615
- Fax
- QQ3095748324
- sales@run-biotech.com
- Country
- China
- ProdList
- 2339
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 13391076197
- tombiopharma@163.com
- Country
- China
- ProdList
- 4987
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 0512-63009836 18994340901
- Fax
- 0512-63006936
- helen@struchem.com
- Country
- China
- ProdList
- 3981
- Advantage
- 60
- Tel
- 28-87999436 02887999436
- Fax
- QQ:2746983436
- sales@sano-chem.com
- Country
- China
- ProdList
- 3795
- Advantage
- 55
- Tel
- 13817485796
- Fax
- QQ:895624079
- tim@wisacheampharm.com
- Country
- China
- ProdList
- 3592
- Advantage
- 58
View Lastest Price from spiro<3.3>heptane-3-carboxylic acid manufacturers
- Product
- Spiro[3.3]heptane-2-carboxylic acid 28114-87-6
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-05
- Product
- spiro<3.3>heptane-3-carboxylic acid 28114-87-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-07