Uses
ChemicalBook > CAS DataBase List > spiro<3.3>heptane-3-carboxylic acid

spiro<3.3>heptane-3-carboxylic acid

Uses
Product Name
spiro<3.3>heptane-3-carboxylic acid
CAS No.
28114-87-6
Chemical Name
spiro<3.3>heptane-3-carboxylic acid
Synonyms
3.3>spiro<heptane-3-carboxylic acid;spiro<3.3>heptane-3-carboxylic acid;Spiro[3.3]heptane-2-carboxylic acid - S11733;Spiro[3.3]heptane-2-carboxylic acid (7CI, 8CI, 9CI, ACI)
CBNumber
CB82655343
Molecular Formula
C8H12O2
Formula Weight
140.18
MOL File
28114-87-6.mol
More
Less

spiro<3.3>heptane-3-carboxylic acid Property

Melting point:
25 °C
Boiling point:
256.8±8.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
form 
liquid
pka
4.77±0.20(Predicted)
color 
Colourless
InChI
InChI=1S/C8H12O2/c9-7(10)6-4-8(5-6)2-1-3-8/h6H,1-5H2,(H,9,10)
InChIKey
FUQHLUSGMOSPRQ-UHFFFAOYSA-N
SMILES
C1C2(CCC2)CC1C(O)=O
More
Less

Safety

HS Code 
2916200090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TRC
Product number
S682525
Product name
Spiro[3.3]heptane-2-carboxylicacid
Packaging
25mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1052105
Product name
SPIRO[3.3]HEPTANE-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$452.05
Updated
2021/12/16
SynQuest Laboratories
Product number
2221-1-28
Product name
Spiro[3.3]heptane-2-carboxylic acid
Packaging
1g
Price
$525
Updated
2021/12/16
Matrix Scientific
Product number
113256
Product name
Spiro[3.3]heptane-2-carboxylic acid
Packaging
1g
Price
$851
Updated
2021/12/16
AK Scientific
Product number
4504AJ
Product name
Spiro[3.3]heptane-2-carboxylicacid
Packaging
5g
Price
$1451
Updated
2021/12/16
More
Less

spiro<3.3>heptane-3-carboxylic acid Chemical Properties,Usage,Production

Uses

Spiro[3.3]heptane-2-carboxylic acid is a carboxylic acid derivative that can be used as a pharmaceutical intermediate.

Synthesis

64775-97-9

28114-87-6

The general procedure for the synthesis of spiro[3.3]heptane-2,2-dicarboxylic acid from spiro[3.3]heptane-2,2-dicarboxylic acid was as follows: spiro[3.3]heptane-2,2-dicarboxylic acid (1.737 g, 9.43 mmol) was dissolved in pyridine (20 mL) and the reaction was heated at 115 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated to dryness in a rotary evaporator. The resulting residue was treated with 6 M aqueous hydrochloric acid and subsequently extracted with dichloromethane (3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated to dryness to afford spiro[3.3]heptane-2-carboxylic acid (1.21 g, 92% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 11.98 (s, 1H), 2.85 (m, 1H), 2.15-2.03 (m, 4H), 1.96 (t, J = 7.3 Hz, 2H), 1.84 (t, J = 7.3 Hz, 2H), 1.76-1.70 (m, 2H).

References

[1] Patent: US2014/275080, 2014, A1. Location in patent: Paragraph 0368
[2] Justus Liebigs Annalen der Chemie, 1961, vol. 648, p. 36 - 50

spiro<3.3>heptane-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

spiro<3.3>heptane-3-carboxylic acid Suppliers

China 73 India 1 United Kingdom 1 United States 6 Global 81
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
More
Less

View Lastest Price from spiro<3.3>heptane-3-carboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Spiro[3.3]heptane-2-carboxylic acid 28114-87-6
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-05
Career Henan Chemical Co
Product
spiro<3.3>heptane-3-carboxylic acid 28114-87-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-07

28114-87-6, spiro<3.3>heptane-3-carboxylic acidRelated Search:

Spiro[3.3]Heptan-2-ylmethanol SPIRO[5.5]UNDECANE-2,4-DIONE Spiro[2.3]hexane-5-carboxylic acid, methyl ester SPIRO[4.5]DECANE-7,9-DIONE Methyl-spiro[2.3]hex-5-yl-amine SPIRO[2.3]HEXANE-5-CARBOXYLIC ACID spiro[2.5]octan-5,7-dione SPIRO[3.5]NONANE-6,8-DIONE 2-AMINOSPIRO[3.3]HEPTANE Spiro[2.3]hex-5-ylamine spiro[3.3]heptan-2-amine hydrochloride Spiro[3.5]nonan-7-ol Spiro[2.5]octane-6-carboxylic acid SPIRO[2.2]PENTANE-1-CARBOXYLIC ACID Spiro[2.5]octane-4,6-dione spiro[3.5]nonan-2-one Spiro[3.3]?heptane-?2,?2-?dicarboxylic acid, 2,?2-?bis(1-?methylethyl) ester spiro[2.4]heptan-7-one

  • spiro<3.3>heptane-3-carboxylic acid
  • Spiro[3.3]heptane-2-carboxylic acid - S11733
  • Spiro[3.3]heptane-2-carboxylic acid (7CI, 8CI, 9CI, ACI)
  • 3.3&gt
  • heptane-3-carboxylic acid
  • spiro&lt
  • 28114-87-6
  • 28114-87-7