ALPHA-BENZOIN OXIME
- Product Name
- ALPHA-BENZOIN OXIME
- CAS No.
- 441-38-3
- Chemical Name
- ALPHA-BENZOIN OXIME
- Synonyms
- CUPRON;CUPRONE;NSC 659;usaffa-5;CUPRON GR;benzoinoxim;BENZOIN OXIME;alpha-benzoin;à-benzoin oxime;BENZOIN A-OXIME
- CBNumber
- CB8267142
- Molecular Formula
- C14H13NO2
- Formula Weight
- 227.26
- MOL File
- 441-38-3.mol
ALPHA-BENZOIN OXIME Property
- Melting point:
- 153-155 °C(lit.)
- Boiling point:
- 368.97°C (rough estimate)
- Density
- 1.13
- vapor density
- 7.9 (vs air)
- refractive index
- 1.5780 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- ethanol: 0.1 g/mL, clear
- pka
- 10.92±0.40(Predicted)
- form
- Crystalline Powder
- color
- White to almost white
- Odor
- Odorless
- optical activity
- 0.2°(C=0.01g/mI, CHCL3, 20°C, 589nm)
- Water Solubility
- Slightly soluble in water
- Sensitive
- Light Sensitive
- Merck
- 14,1094
- BRN
- 2051941
- Stability:
- Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 441-38-3(CAS DataBase Reference)
- EPA Substance Registry System
- Ethanone, 2-hydroxy-1,2-diphenyl-, oxime (441-38-3)
N-Bromosuccinimide Price
- Product number
- B8908
- Product name
- α-Benzoin oxime
- Purity
- 98%
- Packaging
- 25g
- Price
- $102
- Updated
- 2025/07/31
- Product number
- B0081
- Product name
- alpha-Benzoin Oxime
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 25g
- Price
- $61
- Updated
- 2025/07/31
- Product number
- B0081
- Product name
- alpha-Benzoin Oxime
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 500g
- Price
- $685
- Updated
- 2025/07/31
- Product number
- B204020
- Product name
- a-BenzoinOxime
- Packaging
- 50g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB34688
- Product name
- a-Benzoin oxime
- Packaging
- 100g
- Price
- $100
- Updated
- 2021/12/16
ALPHA-BENZOIN OXIME Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Safety Profile
Poison by intraperitoneal route.Mildly toxic by ingestion. An eye irritant. When heated todecomposition it emits toxic fumes of NOx.
Synthesis
119-53-9
441-38-3
General procedure for the synthesis of α-benzoin oxime (copper reagent) from benzene diphosgene: benzene diphosgene (21.2 g, 0.1 mol) was dissolved with NH4OH-HCl (21 g, 0.3 mol) in 300 mL of ethanol. 41.5 mL of triethylamine was added slowly and dropwise to the reaction system, warmed to 75 °C and refluxed for 24 hours. The progress of the reaction was monitored by thin layer chromatography (TLC), and after the disappearance of the raw material point, 300 mL of water was added and extracted three times with dichloromethane. The organic phases were combined, dried over anhydrous sodium sulfate and filtered, and the solvent was removed by rotary evaporation to give about 18 g of the benzene diphenoxime compound in 79% yield. 2.4 g of 10% Pd/C catalyst with a small amount of 3% hydrochloric acid-ethanol solution (10 mL HCl-EtOH) was added to the reaction flask and activated by passing hydrogen gas. Benzene coupling oxime (12.0 g, 52.5 mmol) obtained in the previous step was dissolved in 80 mL of ethanol and slowly added dropwise to the reaction flask and reacted overnight, the system was observed to become viscous. After adding 300 mL of water and filtering, the pH of the filtrate was adjusted to 8 with concentrated ammonia and 9.2 g of 1,2-diphenylamino alcohol solid was precipitated in 82% yield.
Purification Methods
Crystallise the oxime from diethyl ether. It is used for the spectroscopic determination of Cu2+, Pd2+, Pt4+, Rh3+ and V5+ [Singh et al. Talanta 26 425 1979, Beilstein 8 IV 1282.]
References
[1] Patent: CN104945345, 2017, B. Location in patent: Paragraph 0105; 0107-0109
[2] Journal of the Chemical Society, 1909, vol. 95, p. 1597
[3] Heterocycles, 2000, vol. 52, # 3, p. 1359 - 1370
[4] Oriental Journal of Chemistry, 2014, vol. 30, # 3, p. 1343 - 1348
ALPHA-BENZOIN OXIME Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ALPHA-BENZOIN OXIME manufacturers
- Product
- alpha-Benzoin oxime 441-38-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 3500kg/month
- Release date
- 2021-09-10
- Product
- ALPHA-BENZOIN OXIME 441-38-3
- Price
- US $1.00-100.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 300KG
- Release date
- 2024-07-26
- Product
- ALPHA-BENZOIN OXIME 441-38-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27