1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE
- Product Name
- 1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE
- CAS No.
- 84478-76-2
- Chemical Name
- 1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE
- Synonyms
- uoro-2-methoxy-4-nitrobenzene;2-CHLORO-4-FLUORO-5-NITROANISOLE;4-Chloro-2-fluoro-5-methoxy-1-nitrobenzene;1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE;Benzene, 1-chloro-5-fluoro-2-methoxy-4-nitro-;1-Chloro-5-fluoro-2-methoxy-4-nitrobenzene, 2-Chloro-4-fluoro-5-nitrophenyl methyl ether
- CBNumber
- CB8267243
- Molecular Formula
- C7H5ClFNO3
- Formula Weight
- 205.57
- MOL File
- 84478-76-2.mol
1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE Property
- Melting point:
- 72-75°C
- Boiling point:
- 307.9±37.0 °C(Predicted)
- Density
- 1.453
- storage temp.
- Sealed in dry,Room Temperature
- form
- Solid
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 84478-76-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- HazardClass
- IRRITANT
- HS Code
- 2909309090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- C584995
- Product name
- 1-Chloro-5-fluoro-2-methoxy-4-nitrobenzene
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FC103325
- Product name
- 2-Chloro-4-fluoro-5-nitroanisole
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FC103325
- Product name
- 2-Chloro-4-fluoro-5-nitroanisole
- Packaging
- 2g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 045411
- Product name
- 1-Chloro-5-fluoro-2-methoxy-4-nitrobenzene
- Purity
- >95%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
- Product number
- 4654-7-01
- Product name
- 2-Chloro-4-fluoro-5-nitroanisole
- Packaging
- 1g
- Price
- $32
- Updated
- 2021/12/16
1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE Chemical Properties,Usage,Production
Synthesis
84478-75-1
74-88-4
84478-76-2
Potassium carbonate (18 g, 131 mmol) and iodomethane (8.0 mL, 131 mmol) were added to a solution of 2-chloro-4-fluoro-5-nitrophenol (5.0 g, 26.1 mmol) in acetone (100 mL) and stirred at room temperature. The reaction mixture was stirred at room temperature for 2 h. The progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the solvent was removed by evaporation under reduced pressure. The residue was diluted with distilled water (100 mL) and extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, washed sequentially with distilled water (100 mL) and saturated saline (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 2-chloro-4-fluoro-5-nitroanisole as a yellow solid. Yield: 5.0 g (93%). 1H NMR (400 MHz, DMSO-d6): δ 7.94-7.97 (m, 1H), 7.81-7.83 (m, 1H), 3.95 (s, 3H).
References
[1] Patent: WO2018/37223, 2018, A1. Location in patent: Page/Page column 206; 207
[2] Patent: US5136868, 1992, A
[3] Patent: US4427438, 1984, A
[4] Patent: US2004/162282, 2004, A1
[5] Patent: US2009/143367, 2009, A1. Location in patent: Page/Page column 37-38
1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE manufacturers
- Product
- 1-CHLORO-5-FLUORO-2-METHOXY-4-NITROBENZENE 84478-76-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-12