ChemicalBook > CAS DataBase List > 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)

Product Name: 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
CAS No.: 33985-68-1
Chemical Name: 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
Synonyms: C-DIM5;DIM-C-pPhOMe;DIM C pPhOMe;DIM-C-pPhOCH3;C-DIM5 ，S0149;DIM-C-pPhOCH3(C-DIM5);DIM-C-pPhOCH3 >=98% (HPLC);DIM-C-pPhOCH3, 10 mM in DMSO;Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane;1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane
CBNumber: CB82682260
Molecular Formula: C24H20N2O
Formula Weight: 352.43
MOL File: 33985-68-1.mol

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3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Property

Melting point:: 187-189 °C
Boiling point:: 592.7±50.0 °C(Predicted)
Density: 1.251±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥30mg/mL
form: powder
pka: 16.63±0.30(Predicted)
color: off-white to light yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D7946
Product name: DIM-C-pPhOCH3
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $117
Updated: 2025/07/31

Sigma-Aldrich

Product number: D7946
Product name: DIM-C-pPhOCH3
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $476
Updated: 2025/07/31

Cayman Chemical

Product number: 27980
Product name: C-DIM5
Packaging: 5mg
Price: $105
Updated: 2024/03/01

Cayman Chemical

Product number: 27980
Product name: C-DIM5
Packaging: 25mg
Price: $420
Updated: 2024/03/01

Cayman Chemical

Product number: 27980
Product name: C-DIM5
Packaging: 1mg
Price: $32
Updated: 2024/03/01

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3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Chemical Properties,Usage,Production

Uses

[Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane, is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.

Biological Activity

DIM-C-pPhOCH3 is a Nerve Growth Factor-Induced Bα (NGFI-Bα, Nur77) agonist

in vivo

DIM-C-pPhOCH₃ (25 mg/kg/d) also inhibits tumor growth in athymic nude mice bearing RKO cell xenografts. The effects of DIM-C-pPhOCH₃ (25 mg/kg/d) on colon tumor growth are also investigated in athymic nude mice bearing RKO cell xenografts. Treatment with the DIM-C-pPhOCH₃ significantly decreases tumor volumes and final tumor weights compared with corn oil controls^[1].

IC 50

Nur77/NR4A1

storage

Store at -20°C

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Preparation Products And Raw materials

Raw materials

Preparation Products

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33985-68-1, 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)Related Search:

2-Phenylindole

DIM-C-pPhOCH3

C-DIM5

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)

1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane

DIM-C-pPhOCH3(C-DIM5)

1H-Indole, 3,3'-[(4-methoxyphenyl)methylene]bis-

DIM-C-pPhOCH3 >=98% (HPLC)

Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane

Inhibitor,DIM-C-pPhOCH-3,DIM C pPhOCH3,DIMCpPhOCH3,inhibit

DIM C pPhOMe

DIM-C-pPhOMe

DIM-C-pPhOCH3, 10 mM in DMSO

C-DIM5 ，S0149

33985-68-1