1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride

Product Name: 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride
CAS No.: 956025-47-1
Chemical Name: 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride
Synonyms: 100671;1-Naphthyl PP1 HCl;Reaxys ID: 15596117;1-NA-PP 1 hydrochloride;1-Naphthyl PP1(1-NA-PP1) HCl;1-Naphthyl PP1 (hydrochloride);4-d]pyriMidin-4-aMine hydrochloride;1-Naphthyl PP1 hydrochloride, 10 mM in DMSO;1-Tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3;1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride
CBNumber: CB82684370
Molecular Formula: C19H20ClN5
Formula Weight: 353.8486
MOL File: 956025-47-1.mol

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1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride Property

storage temp.: Store at -20°C
solubility: DMSO : ≥ 73 mg/mL (206.30 mM)
form: Solid
color: Light yellow to khaki

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-5384
Product name: 1-NaphthylPP1(hydrochloride)
Purity: 99.82%
Packaging: 10mg
Price: $158
Updated: 2021/12/16

ChemScene

Product number: CS-5384
Product name: 1-NaphthylPP1(hydrochloride)
Purity: 99.82%
Packaging: 50mg
Price: $637
Updated: 2021/12/16

ChemScene

Product number: CS-5384
Product name: 1-NaphthylPP1(hydrochloride)
Purity: 99.82%
Packaging: 5mg
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-5384
Product name: 1-NaphthylPP1(hydrochloride)
Purity: 99.82%
Packaging: 100mg
Price: $1080
Updated: 2021/12/16

Matrix Scientific

Product number: 120655
Product name: 1-tert-Butyl-3-(naphthalen-1-yl)-1H-pyrazolo-[3,4-d]pyrimidin-4-amine hydrochloride
Purity: 97%
Packaging: 100mg
Price: $1584
Updated: 2021/12/16

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1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride Chemical Properties,Usage,Production

Uses

1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 hydrochloride inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively[1].

References

[1] Tandon M, et al. New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells. PLoS One. 2013 Sep 23;8(9):e75601. DOI:10.1371/journal.pone.0075601
[2] Bishop AC, et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 2000 Sep 21;407(6802):395-401. DOI:10.1038/35030148

1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride Suppliers

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956025-47-1, 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochlorideRelated Search:

Pyrazole 2-Chloro-2-methylpropane 2-Bromo-2-methylpropane 3,3-Dimethyl-1-butyne

1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride

100671

Reaxys ID: 15596117

1-Tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3

1-TERT-BUTYL-3-(NAPHTHALEN-1-YL)-1H-PYRAZOLO[3;4-D]PYRIMIDIN-4-AMINE HYDROCHLORIDE;1-NA-PP 1 HYDROCHLORIDE

4-d]pyriMidin-4-aMine hydrochloride

1-Naphthyl PP1 HCl

1-Naphthyl PP1 (hydrochloride)

1-NA-PP 1 hydrochloride

1-Naphthyl PP1(1-NA-PP1) HCl

1 Naphthyl PP1 hydrochloride,Src,1Naphthyl PP1 hydrochloride,1-Naphthyl PP-1 hydrochloride,1-Naphthyl PP1,Inhibitor,inhibit

1-Naphthyl PP1 hydrochloride, 10 mM in DMSO

956025-47-1

C19H19N5ClH