2-BroMo-4-fluoro-5-nitrobenzoic Acid
- Product Name
- 2-BroMo-4-fluoro-5-nitrobenzoic Acid
- CAS No.
- 1036389-83-9
- Chemical Name
- 2-BroMo-4-fluoro-5-nitrobenzoic Acid
- Synonyms
- 2-BroMo-4-fluoro-5-nitrobenzoic Acid;Benzoic acid, 2-bromo-4-fluoro-5-nitro-
- CBNumber
- CB82709451
- Molecular Formula
- C7H3BrFNO4
- Formula Weight
- 264.01
- MOL File
- 1036389-83-9.mol
2-BroMo-4-fluoro-5-nitrobenzoic Acid Property
- Boiling point:
- 379.8±42.0 °C(Predicted)
- Density
- 1.967±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.25±0.12(Predicted)
- Appearance
- Off-white to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B685725
- Product name
- 2-Bromo-4-fluoro-5-nitrobenzoicAcid
- Packaging
- 10g
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- CS-W006521
- Product name
- 2-Bromo-4-fluoro-5-nitrobenzoicacid
- Packaging
- 250mg
- Price
- $51
- Updated
- 2021/12/16
- Product number
- CS-W006521
- Product name
- 2-Bromo-4-fluoro-5-nitrobenzoicacid
- Packaging
- 1g
- Price
- $129
- Updated
- 2021/12/16
- Product number
- CS-W006521
- Product name
- 2-Bromo-4-fluoro-5-nitrobenzoicacid
- Packaging
- 1g
- Price
- $129
- Updated
- 2021/12/16
- Product number
- HCH0068868
- Product name
- 2-BROMO-4-FLUORO-5-NITROBENZOIC ACID
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $253.05
- Updated
- 2021/12/16
2-BroMo-4-fluoro-5-nitrobenzoic Acid Chemical Properties,Usage,Production
Uses
2-Bromo-4-fluoro-5-nitrobenzoic Acid, is a halogenated derivative of benzoic acid. It can be used for the synthesis of various pharmaceutical compounds, such as amino acid derivatives acting as anticoagulants.
Synthesis
1006-41-3
1036389-83-9
Fuming nitric acid (4 mL, 45.60 mmol) was slowly added dropwise to a mixed solution containing 2-bromo-4-fluorobenzoic acid (10 g, 45.66 mmol) and concentrated sulfuric acid (34 mL) under cooling conditions in an ice bath. Upon completion of the reaction, the reaction mixture was poured into ice water and stirred vigorously for 1 hour. The precipitate was collected by filtration, washed with ice water and dried to give 10.40 g of white solid product. It was further washed with water and evaporated to dryness to finally obtain 2-bromo-4-fluoro-5-nitrobenzoic acid in white solid form in 86% yield.
References
[1] Patent: CN106146474, 2016, A. Location in patent: Paragraph 0097 - 0098
[2] Patent: US2018/291002, 2018, A1. Location in patent: Paragraph 0444; 0445
[3] Patent: WO2017/176812, 2017, A1. Location in patent: Paragraph 0451
[4] Patent: WO2008/79836, 2008, A2. Location in patent: Page/Page column 86-87
2-BroMo-4-fluoro-5-nitrobenzoic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-BroMo-4-fluoro-5-nitrobenzoic Acid Suppliers
- Tel
- --
- Fax
- --
- enquiries@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6401
- Advantage
- 74
View Lastest Price from 2-BroMo-4-fluoro-5-nitrobenzoic Acid manufacturers
- Product
- 2-BroMo-4-fluoro-5-nitrobenzoic Acid 1036389-83-9
- Price
- US $8.00/KG
- Min. Order
- 1g
- Purity
- Min98% HPLC/gc
- Supply Ability
- g/kg/ton
- Release date
- 2020-11-04