ChemicalBook > CAS DataBase List > NIBR189
NIBR189
- Product Name
- NIBR189
- CAS No.
- 1599432-08-2
- Chemical Name
- NIBR189
- Synonyms
- CS-1583;NIBR189;NIBR-189; NIBR 189;(E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one;(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one;(2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-, (2E)-;Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U937,NIBR-189,G protein,inhibit,migration
- CBNumber
- CB82715658
- Molecular Formula
- C21H21BrN2O3
- Formula Weight
- 429.31
- MOL File
- 1599432-08-2.mol
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NIBR189 Property
- Boiling point:
- 639.7±55.0 °C(Predicted)
- Density
- 1.403±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at -20°C
- solubility
- ≥42.9 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
- form
- solid
- pka
- -0.86±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 18792
- Product name
- NIBR189
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18792
- Product name
- NIBR189
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18792
- Product name
- NIBR189
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $172
- Updated
- 2024/03/01
Tocris
- Product number
- 5203
- Product name
- NIBR189
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $193
- Updated
- 2021/12/16
Tocris
- Product number
- 5203
- Product name
- NIBR189
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $789
- Updated
- 2021/12/16
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NIBR189 Chemical Properties,Usage,Production
Uses
(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one recently known as NIBR 189, is a selective Epstein-barr virus-induced gene 2 (EBI-2) receptor antagonist, resulting in a modulation of immune responses related to auto-immune diseases.
Biological Activity
nibr189 is a small molecule antagonist of the epstein-barr virus-induced gene 2 (ebi2; gpr183) receptor with ic50 of 16 nm(binding) and 11 nm (functional).
storage
Store at +4°C
NIBR189 Preparation Products And Raw materials
Raw materials
Preparation Products
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