ChemicalBook > CAS DataBase List > C24-Ceramide

C24-Ceramide

Product Name
C24-Ceramide
CAS No.
34435-05-7
Chemical Name
C24-Ceramide
Synonyms
C24 CERAMIDE;LIGNOCERIC CERAMIDE;N-TETRACOSANOYL-D-ERYTHRO-SPHINGOSINE;TETRACOSENAMIDE;C24-D-ERYTHRO-CERAMIDE;N-Lignoceroylsphingosine;N-MYRISTOYL-D-SPHINGOSINE;N-TETRACOSANOYLSPHINGOSINE;N-MYRISTOYL-D-ERYTHRO-SPHINGOSINE;N-((2R,3S,E)-1,3-Dihydroxyoctadec-4-en-2-yl)tetracosanamide
CBNumber
CB8272483
Molecular Formula
C42H83NO3
Formula Weight
650.11
MOL File
34435-05-7.mol
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C24-Ceramide Property

Melting point:
94-96
Boiling point:
750.0±60.0 °C(Predicted)
Density 
0.906±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Sparingly)
form 
Solid
pka
13.54±0.20(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
1mg
Price
$23
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
5mg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
10mg
Price
$180
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
25mg
Price
$393
Updated
2024/03/01
TRC
Product number
C263450
Product name
C24Ceramide
Packaging
5mg
Price
$90
Updated
2021/12/16
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C24-Ceramide Chemical Properties,Usage,Production

Description

Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase. C24 Ceramide (d18:1/24:0) is one of the most abundant naturally occurring ceramides. Ceramides mediate many diverse biological activities, as has been demonstrated in studies utilizing cell-permeable ceramide analogs. A few of the processes regulated by ceramides include apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain.

Chemical Properties

Crystalline Solid

Uses

Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of phospholipase C, appropriately named sphingomyelinase.

Definition

ChEBI: N-tetracosanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as tetracosanoyl. It has a role as a mouse metabolite. It is a N-acylsphingosine, a Cer(d42:1) and a N-(very-long-chain fatty acyl)-sphingoid base. It is functionally related to a tetracosanoic acid.

References

[1] MING GU . Ceramide Profiling of Complex Lipid Mixtures by Electrospray Ionization Mass Spectrometry[J]. Analytical biochemistry, 1997, 244 2: Pages 347-356. DOI: 10.1006/abio.1996.9915
[2] R B CLAYTON. Stimulation of erythroblast maturation in vitro by sphingolipids.[J]. Journal of Lipid Research, 1974, 15 6: 557-562.
[3] W KRIVIT  S H. Identification and quantitation of free ceramides in human platelets.[J]. Journal of Lipid Research, 1972, 13 4: 525-530.
[4] TESTI R. Sphingomyelin breakdown and cell fate[J]. Trends in Biochemical Sciences, 1996, 21 12: Pages 468-471. DOI: 10.1016/s0968-0004(96)10056-6
[5] N AUGé. The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation.[J]. The Journal of Biological Chemistry, 1996, 271 32: 19251-19255. DOI: 10.1074/jbc.271.32.19251
[6] T I GUDZ  C L H  K Y Tserng. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide.[J]. The Journal of Biological Chemistry, 1997, 272 39: 24154-24158. DOI: 10.1074/jbc.272.39.24154

C24-Ceramide Preparation Products And Raw materials

Raw materials

Preparation Products

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34435-05-7, C24-CeramideRelated Search:


  • C24-D-ERYTHRO-CERAMIDE
  • C24 CERAMIDE
  • LIGNOCERIC CERAMIDE
  • TETRACOSENAMIDE
  • N-TETRACOSANOYLSPHINGOSINE
  • N-TETRACOSANOYL-D-ERYTHRO-SPHINGOSINE
  • N-MYRISTOYL-D-ERYTHRO-SPHINGOSINE
  • N-MYRISTOYL-D-SPHINGOSINE
  • N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-Tetracosanamide
  • N-Lignoceroylsphingosine
  • Tetracosanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
  • N-((2R,3S,E)-1,3-Dihydroxyoctadec-4-en-2-yl)tetracosanamide
  • 34435-05-7
  • Mixed Fatty Acids
  • Activators
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Inhibitors
  • Protein Kinase Inhibitors and Activators