FMoc-α-Me-Lys(Boc)-OH
- Product Name
- FMoc-α-Me-Lys(Boc)-OH
- CAS No.
- 1202003-49-3
- Chemical Name
- FMoc-α-Me-Lys(Boc)-OH
- Synonyms
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid;Fmoc-a-Me-Lys(Boc)-OH;Fmoc-α-Me-Lys(Boc)-OH;Fmoc-alpha-Me-Lys(Boc)-OH;Fmoc-alpha-Me-L-Lys(Boc)-OH;Fmoc-α-methyl-L-Lysine(Boc);FMoc-α-Me-Lys(Boc)-OH USP/EP/BP;N6-Boc-N2-Fmoc-alfa-Me--L-Lys-OH;N6-Boc-N2-Fmoc-2-methyl-L-Lysine;(S)-Na-Fmoc-NW-Boc-α-Methyllysine
- CBNumber
- CB82729321
- Molecular Formula
- C27H34N2O6
- Formula Weight
- 482.57
- MOL File
- 1202003-49-3.mol
FMoc-α-Me-Lys(Boc)-OH Property
- Boiling point:
- 687.9±55.0 °C(Predicted)
- Density
- 1.196±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.92±0.41(Predicted)
- form
- powder
- color
- white
- InChI
- InChI=1S/C27H34N2O6/c1-26(2,3)35-24(32)28-16-10-9-15-27(4,23(30)31)29-25(33)34-17-22-20-13-7-5-11-18(20)19-12-6-8-14-21(19)22/h5-8,11-14,22H,9-10,15-17H2,1-4H3,(H,28,32)(H,29,33)(H,30,31)/t27-/m0/s1
- InChIKey
- MYQXEVZHWDILHG-MHZLTWQESA-N
- SMILES
- C(O)(=O)[C@](C)(CCCCNC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-40-67
- Safety Statements
- 23-24/25-36/37
- TSCA
- No
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P281Use personal protective equipment as required.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F647540
- Product name
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoicAcid
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 0415AP
- Product name
- Fmoc-alpha-Me-Lys(Boc)-OH
- Packaging
- 25mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 300598
- Product name
- (S)-Nα-Fmoc-Nω-Boc-α-Methyllysine, 98%
- Packaging
- 100mg
- Price
- $121
- Updated
- 2021/12/16
- Product number
- AS115441
- Product name
- (S)-Na-Fmoc-Nw-Boc-alpha-methyllysine
- Purity
- 97+% ee
- Packaging
- 100mg
- Price
- $194
- Updated
- 2021/12/16
- Product number
- 0415AP
- Product name
- Fmoc-alpha-Me-Lys(Boc)-OH
- Packaging
- 100mg
- Price
- $217
- Updated
- 2021/12/16
FMoc-α-Me-Lys(Boc)-OH Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder.
Uses
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid is a reagent in the preparation/biological evaluation of a vapreotide analogs containing (S)?-?α-?methyl-?lysine.
Synthesis
Benzyl (2R,3S)-(?)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (4) was successively alkylated with methyl iodide and 1,4-diiodobutane using a base. In each alkylation step anti-alkylated product formed exclusively. The iodo group was displaced with azide, which served as a precursor for the side-chain amino function. Catalytic hydrogenation with concomitant cleavage of the chiral auxiliary afforded (L)-α-Me-Lys-OH (9) in a total of four steps in good yield. (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained from 9 via regioselective benzyloxycarbonylation. Alternately, (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained via Staudinger reduction of azide (8) in a total of six steps in good yield.
FMoc-α-Me-Lys(Boc)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
FMoc-α-Me-Lys(Boc)-OH Suppliers
- Tel
- +1 (888) 615-9178 / (561) 791-8787
- Fax
- +1 (561) 791-8728
- service@chempep.com
- Country
- United States
- ProdList
- 2138
- Advantage
- 57
- Tel
- 16314854226; +16314854226
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19741
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@synthonix.com
- Country
- United States
- ProdList
- 6872
- Advantage
- 58
View Lastest Price from FMoc-α-Me-Lys(Boc)-OH manufacturers
- Product
- FMoc-α-Me-Lys(Boc)-OH 1202003-49-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-08