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FMoc-α-Me-Lys(Boc)-OH

Product Name
FMoc-α-Me-Lys(Boc)-OH
CAS No.
1202003-49-3
Chemical Name
FMoc-α-Me-Lys(Boc)-OH
Synonyms
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid;Fmoc-a-Me-Lys(Boc)-OH;Fmoc-α-Me-Lys(Boc)-OH;Fmoc-alpha-Me-Lys(Boc)-OH;Fmoc-alpha-Me-L-Lys(Boc)-OH;Fmoc-α-methyl-L-Lysine(Boc);FMoc-α-Me-Lys(Boc)-OH USP/EP/BP;N6-Boc-N2-Fmoc-alfa-Me--L-Lys-OH;N6-Boc-N2-Fmoc-2-methyl-L-Lysine;(S)-Na-Fmoc-NW-Boc-α-Methyllysine
CBNumber
CB82729321
Molecular Formula
C27H34N2O6
Formula Weight
482.57
MOL File
1202003-49-3.mol
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FMoc-α-Me-Lys(Boc)-OH Property

Boiling point:
687.9±55.0 °C(Predicted)
Density 
1.196±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.92±0.41(Predicted)
form 
powder
color 
white
InChI
InChI=1S/C27H34N2O6/c1-26(2,3)35-24(32)28-16-10-9-15-27(4,23(30)31)29-25(33)34-17-22-20-13-7-5-11-18(20)19-12-6-8-14-21(19)22/h5-8,11-14,22H,9-10,15-17H2,1-4H3,(H,28,32)(H,29,33)(H,30,31)/t27-/m0/s1
InChIKey
MYQXEVZHWDILHG-MHZLTWQESA-N
SMILES
C(O)(=O)[C@](C)(CCCCNC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-40-67
Safety Statements 
23-24/25-36/37
TSCA 
No
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P281Use personal protective equipment as required.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F647540
Product name
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoicAcid
Packaging
10mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
0415AP
Product name
Fmoc-alpha-Me-Lys(Boc)-OH
Packaging
25mg
Price
$95
Updated
2021/12/16
ChemSupplyAustralia
Product number
300598
Product name
(S)-Nα-Fmoc-Nω-Boc-α-Methyllysine, 98%
Packaging
100mg
Price
$121
Updated
2021/12/16
Activate Scientific
Product number
AS115441
Product name
(S)-Na-Fmoc-Nw-Boc-alpha-methyllysine
Purity
97+% ee
Packaging
100mg
Price
$194
Updated
2021/12/16
AK Scientific
Product number
0415AP
Product name
Fmoc-alpha-Me-Lys(Boc)-OH
Packaging
100mg
Price
$217
Updated
2021/12/16
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FMoc-α-Me-Lys(Boc)-OH Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder.

Uses

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid is a reagent in the preparation/biological evaluation of a vapreotide analogs containing (S)?-?α-?methyl-?lysine.

Synthesis

Benzyl (2R,3S)-(?)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (4) was successively alkylated with methyl iodide and 1,4-diiodobutane using a base. In each alkylation step anti-alkylated product formed exclusively. The iodo group was displaced with azide, which served as a precursor for the side-chain amino function. Catalytic hydrogenation with concomitant cleavage of the chiral auxiliary afforded (L)-α-Me-Lys-OH (9) in a total of four steps in good yield. (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained from 9 via regioselective benzyloxycarbonylation. Alternately, (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained via Staudinger reduction of azide (8) in a total of six steps in good yield.

FMoc-α-Me-Lys(Boc)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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FMoc-α-Me-Lys(Boc)-OH Suppliers

ChemPep, Inc.
Tel
+1 (888) 615-9178 / (561) 791-8787
Fax
+1 (561) 791-8728
Email
service@chempep.com
Country
United States
ProdList
2138
Advantage
57
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
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View Lastest Price from FMoc-α-Me-Lys(Boc)-OH manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
FMoc-α-Me-Lys(Boc)-OH 1202003-49-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-08

1202003-49-3, FMoc-α-Me-Lys(Boc)-OHRelated Search:


  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid
  • N6-[(1,1-Dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-lysine
  • (S)-N-ALPHA-FMOC-N-EPSILON-BOC-ALPHA-METHYLLYSINE
  • (S)-NΑ-FMOC-NΩ-BOC-Α-METHYLLYSINE
  • (S)-Na-Fmoc-NW-Boc-α-Methyllysine
  • Fmoc-alpha-Me-L-Lys(Boc)-OH
  • (2S)-6-{[(tert-butoxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylhexanoic acid
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Lys(Boc)-OH
  • N6-Boc-N2-Fmoc-alfa-Me--L-Lys-OH
  • (S)-N-ALPHA-FMOC-N-EPSILON-BOC-ALPHA-METHYLLYSINE, >97%
  • Fmoc-a-Me-Lys(Boc)-OH
  • Fmoc-α-methyl-L-Lysine(Boc)
  • (S)-Na-Fmoc-Nw-Boc-A-Methyllysine
  • Fmoc-alpha-Me-Lys(Boc)-OH
  • L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-
  • N6-Boc-N2-Fmoc-2-methyl-L-Lysine
  • Fmoc-α-Me-Lys(Boc)-OH
  • FMoc-α-Me-Lys(Boc)-OH USP/EP/BP
  • N-α-(9-Fluorenylmethoxycarbonyl)-N-ε-(t-butoxycarbonyl)-α-methyl-L-lysine
  • (S)-Na-Fmoc-NW-Boc-α-Methyllysine
  • 1202003-49-3
  • 1202003-41-3
  • α-Methyl Amino Acids