E-7449

Product Name: E-7449
CAS No.: 1140964-99-3
Chemical Name: E-7449
Synonyms: E7449;E-7449;E7449;E 7449;UNII-9X5A2QIA7C;Stenoparib (E7449);Stenoparib, E7449, 2X-121;Stenoparib（E7449，2X-121，MGI25036）;E7449,PARP,Inhibitor,inhibit,E 7449,E-7449,poly ADP ribose polymerase;8-(Isoindolin-2-ylmethyl)-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one;8-(1,3-dihydro-isoindol-2-ylmethyl)-2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one
CBNumber: CB82729361
Molecular Formula: C18H15N5O
Formula Weight: 317.34
MOL File: 1140964-99-3.mol

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E-7449 Property

Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:0.2(Max Conc. mg/mL);0.63(Max Conc. mM)
form: A crystalline solid
pka: 9.51±0.20(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 5mg
Price: $145
Updated: 2024/03/01

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 10mg
Price: $275
Updated: 2024/03/01

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 25mg
Price: $571
Updated: 2024/03/01

Usbiological

Product number: 447764
Product name: E 7449
Packaging: 1mg
Price: $468
Updated: 2021/12/16

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E-7449 Chemical Properties,Usage,Production

Uses

E 7449 is a dual inhibitor of PARP1/2 and tankyrase1/2 exhibits anti-tumor activity in BRCA-deficient in vivo models. PARP1/2 and tankyrase1/2 are involved with DNA damage and canonical Wnt/β-catenin signaling, respectively.

E-7449 Preparation Products And Raw materials

Raw materials

Preparation Products

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E-7449 Suppliers

China 68 United States 8 Global 76

Deyang Sino Biotech. Co., LTD

Tel: +86-19182167371 +86-19182167371
Email: service@synlord.com
Country: China
ProdList: 101
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4566
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8012
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
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Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
ProdList: 9952
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Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29785
Advantage: 68

1140964-99-3, E-7449Related Search:

E7449

E-7449

8-(1,3-dihydro-isoindol-2-ylmethyl)-2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one

E7449;E 7449

3H-Pyridazino[3,4,5-de]quinazolin-3-one, 8-[(1,3-dihydro-2H-isoindol-2-yl)methyl]-1,2-dihydro-

UNII-9X5A2QIA7C

Stenoparib (E7449)

E7449,PARP,Inhibitor,inhibit,E 7449,E-7449,poly ADP ribose polymerase

Stenoparib, E7449, 2X-121

Stenoparib（E7449，2X-121，MGI25036）

8-(Isoindolin-2-ylmethyl)-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one

1140964-99-3