ChemicalBook > CAS DataBase List > E-7449

E-7449

Product Name
E-7449
CAS No.
1140964-99-3
Chemical Name
E-7449
Synonyms
E7449;E-7449;E7449;E 7449;UNII-9X5A2QIA7C;Stenoparib (E7449);Stenoparib, E7449, 2X-121;Stenoparib(E7449,2X-121,MGI25036);E7449,PARP,Inhibitor,inhibit,E 7449,E-7449,poly ADP ribose polymerase;8-(Isoindolin-2-ylmethyl)-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one;8-(1,3-dihydro-isoindol-2-ylmethyl)-2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one
CBNumber
CB82729361
Molecular Formula
C18H15N5O
Formula Weight
317.34
MOL File
1140964-99-3.mol
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E-7449 Property

Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:0.2(Max Conc. mg/mL);0.63(Max Conc. mM)
form 
A crystalline solid
pka
9.51±0.20(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21658
Product name
E7449
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
21658
Product name
E7449
Purity
≥98%
Packaging
5mg
Price
$145
Updated
2024/03/01
Cayman Chemical
Product number
21658
Product name
E7449
Purity
≥98%
Packaging
10mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
21658
Product name
E7449
Purity
≥98%
Packaging
25mg
Price
$571
Updated
2024/03/01
Usbiological
Product number
447764
Product name
E 7449
Packaging
1mg
Price
$468
Updated
2021/12/16
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E-7449 Chemical Properties,Usage,Production

Uses

E 7449 is a dual inhibitor of PARP1/2 and tankyrase1/2 exhibits anti-tumor activity in BRCA-deficient in vivo models. PARP1/2 and tankyrase1/2 are involved with DNA damage and canonical Wnt/β-catenin signaling, respectively.

E-7449 Preparation Products And Raw materials

Raw materials

Preparation Products

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E-7449 Suppliers

Deyang Sino Biotech. Co., LTD
Tel
+86-19182167371 +86-19182167371
Email
service@synlord.com
Country
China
ProdList
101
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4566
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8012
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2988
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9952
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68

1140964-99-3, E-7449Related Search:


  • E7449
  • E-7449
  • 8-(1,3-dihydro-isoindol-2-ylmethyl)-2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one
  • E7449;E 7449
  • 3H-Pyridazino[3,4,5-de]quinazolin-3-one, 8-[(1,3-dihydro-2H-isoindol-2-yl)methyl]-1,2-dihydro-
  • UNII-9X5A2QIA7C
  • Stenoparib (E7449)
  • E7449,PARP,Inhibitor,inhibit,E 7449,E-7449,poly ADP ribose polymerase
  • Stenoparib, E7449, 2X-121
  • Stenoparib(E7449,2X-121,MGI25036)
  • 8-(Isoindolin-2-ylmethyl)-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one
  • 1140964-99-3