BRD73954

Product Name: BRD73954
CAS No.: 1440209-96-0
Chemical Name: BRD73954
Synonyms: CS-1777;BRD73954;BRD-73954;BRD 73954;N1-hydroxy-N3-phenethylisophthalamide;N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide;1,3-Benzenedicarboxamide, N1-hydroxy-N3-(2-phenylethyl)-;BRD73954, 1-N-hydroxy-3-N-(2-phenylethyl)benzene-1,3-dicarboxamide;N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide BRD73954
CBNumber: CB82730826
Molecular Formula: C16H16N2O3
Formula Weight: 284.31
MOL File: 1440209-96-0.mol

More

Less

BRD73954 Property

Melting point:: 172-175oC
Density: 1.245±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 8.56±0.10(Predicted)
color: Off-White

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1361
Product name: BRD73954
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $129
Updated: 2022/05/15

Sigma-Aldrich

Product number: SML1361
Product name: BRD73954
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $513
Updated: 2022/05/15

Cayman Chemical

Product number: 16919
Product name: BRD73954
Purity: ≥95%
Packaging: 1mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 16919
Product name: BRD73954
Purity: ≥95%
Packaging: 5mg
Price: $356
Updated: 2024/03/01

Cayman Chemical

Product number: 16919
Product name: BRD73954
Purity: ≥95%
Packaging: 10mg
Price: $632
Updated: 2024/03/01

More

Less

BRD73954 Chemical Properties,Usage,Production

Description

BRD73954 is a dual inhibitor of histone deacetylase 6 (HDAC6) and HDAC8 (IC₅₀s = 36 and 120 nM, respectively). It is selective for HDAC6 and -8 over HDAC1-5, -7, and -9 (IC₅₀s = 12, 9, 23, >33, >33, 13, and >33 μM, respectively). BRD73954 (10 μM) increases acetylation of α-tubulin, a known HDAC6 substrate, but not histone H3, a substrate for HDAC1, -2, and -3, in HeLa cells.

Uses

BRD73954 is a small molecule inhibitor which has the ability to inhibit HDAC6 and HDAC8. Affects cell adhesion and mobility in cells.

storage

Store at +4°C

References

[1]. olson de, wagner ff, kaya t, et al. discovery of the first histone deacetylase 6/8 dual inhibitors. j med chem, 2013, 56(11): 4816-4820.

BRD73954 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BRD73954 Suppliers

China 70 India 1 United Kingdom 1 United States 14 Global 86

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4575
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 1004
Advantage: 55

Guangzhou Zhiya Chemdrugs Co.,Ltd

Tel: 18122150900
Fax: QQ:2869377561
Email: sculk28@163.com
Country: China
ProdList: 646
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

More

Less

View Lastest Price from BRD73954 manufacturers

Career Henan Chemical Co

Product: BRD73954 1440209-96-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98-100%
Supply Ability: 1000kg
Release date: 2018-08-20

1440209-96-0, BRD73954Related Search:

N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide

BRD73954

N1-hydroxy-N3-phenethylisophthalamide

N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide BRD73954

BRD73954, 1-N-hydroxy-3-N-(2-phenylethyl)benzene-1,3-dicarboxamide

BRD-73954;BRD 73954

CS-1777

1,3-Benzenedicarboxamide, N1-hydroxy-N3-(2-phenylethyl)-

1440209-96-0

Inhibitors