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BRD73954

Product Name
BRD73954
CAS No.
1440209-96-0
Chemical Name
BRD73954
Synonyms
CS-1777;BRD73954;BRD-73954;BRD 73954;N1-hydroxy-N3-phenethylisophthalamide;N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide;1,3-Benzenedicarboxamide, N1-hydroxy-N3-(2-phenylethyl)-;BRD73954, 1-N-hydroxy-3-N-(2-phenylethyl)benzene-1,3-dicarboxamide;N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide BRD73954
CBNumber
CB82730826
Molecular Formula
C16H16N2O3
Formula Weight
284.31
MOL File
1440209-96-0.mol
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BRD73954 Property

Melting point:
172-175oC
Density 
1.245±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
8.56±0.10(Predicted)
color 
Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1361
Product name
BRD73954
Purity
≥98% (HPLC)
Packaging
5MG
Price
$129
Updated
2022/05/15
Sigma-Aldrich
Product number
SML1361
Product name
BRD73954
Purity
≥98% (HPLC)
Packaging
25MG
Price
$513
Updated
2022/05/15
Cayman Chemical
Product number
16919
Product name
BRD73954
Purity
≥95%
Packaging
1mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
16919
Product name
BRD73954
Purity
≥95%
Packaging
5mg
Price
$356
Updated
2024/03/01
Cayman Chemical
Product number
16919
Product name
BRD73954
Purity
≥95%
Packaging
10mg
Price
$632
Updated
2024/03/01
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BRD73954 Chemical Properties,Usage,Production

Description

BRD73954 is a dual inhibitor of histone deacetylase 6 (HDAC6) and HDAC8 (IC50s = 36 and 120 nM, respectively). It is selective for HDAC6 and -8 over HDAC1-5, -7, and -9 (IC50s = 12, 9, 23, >33, >33, 13, and >33 μM, respectively). BRD73954 (10 μM) increases acetylation of α-tubulin, a known HDAC6 substrate, but not histone H3, a substrate for HDAC1, -2, and -3, in HeLa cells.

Uses

BRD73954 is a small molecule inhibitor which has the ability to inhibit HDAC6 and HDAC8. Affects cell adhesion and mobility in cells.

storage

Store at +4°C

References

[1]. olson de, wagner ff, kaya t, et al. discovery of the first histone deacetylase 6/8 dual inhibitors. j med chem, 2013, 56(11): 4816-4820.

BRD73954 Preparation Products And Raw materials

Raw materials

Preparation Products

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BRD73954 Suppliers

China 69 India 1 United Kingdom 1 United States 14 Global 85
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
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4861
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AdooQ BioScience, LLC
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+1 (866) 930-6790
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+1 (866) 333-9607
Email
info@adooq.com
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United States
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2782
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58
BOC Sciences
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16314854226
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info@bocsci.com
Country
United States
ProdList
9923
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65
Target molecule Corp.
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857-239-0968
Fax
857-239-8801
Email
service1@targetmol.com
Country
United States
ProdList
2559
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60
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
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58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
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58
TargetMol Chemicals Inc.
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Email
support@targetmol.com
Country
United States
ProdList
38632
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58
ApexBio Technology
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sales@apexbt.com
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United States
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Selleck Chemicals LLC
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info@selleckchem.com
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United States
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Cayman Chemical Company
Tel
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Email
cayman@caymanchem.com
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United States
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6213
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Axon Medchem LLC
Tel
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Email
info@axonmedchem.com
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United States
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763
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View Lastest Price from BRD73954 manufacturers

Career Henan Chemical Co
Product
BRD73954 1440209-96-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98-100%
Supply Ability
1000kg
Release date
2018-08-20

1440209-96-0, BRD73954Related Search:


  • N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide
  • BRD73954
  • N1-hydroxy-N3-phenethylisophthalamide
  • N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide BRD73954
  • BRD73954, 1-N-hydroxy-3-N-(2-phenylethyl)benzene-1,3-dicarboxamide
  • BRD-73954;BRD 73954
  • CS-1777
  • 1,3-Benzenedicarboxamide, N1-hydroxy-N3-(2-phenylethyl)-
  • 1440209-96-0
  • Inhibitors