Diphenylphosphinic Chloride
- Product Name
- Diphenylphosphinic Chloride
- CAS No.
- 1499-21-4
- Chemical Name
- Diphenylphosphinic Chloride
- Synonyms
- DPPC;DIPHENYLPHOSPHINIC CHLORIDE;DPP-CL;Ph2POCl;phosphinic chL;Diphenylphoshinic;CHLORODIPHIOSPHINE OXIDE;DIPHENYLPHOSHINIC CHLORIDE;Diphenylphosphinic chlorid;DIPHENYLPHOSPHINYL CHLORIDE
- CBNumber
- CB8273899
- Molecular Formula
- C12H10ClOP
- Formula Weight
- 236.63
- MOL File
- 1499-21-4.mol
Diphenylphosphinic Chloride Property
- Melting point:
- 20°C
- Boiling point:
- 222 °C/16 mmHg (lit.)
- Density
- 1.24 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.609(lit.)
- Flash point:
- 79 °F
- storage temp.
- 2-8°C
- solubility
- soluble in Chloroform, methanol
- form
- Liquid
- Specific Gravity
- 1.24
- color
- Clear colorless to yellow
- Water Solubility
- decomposes
- Sensitive
- Moisture Sensitive
- BRN
- 975191
- CAS DataBase Reference
- 1499-21-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Diphenylphosphinic chloride(1499-21-4)
Safety
- Hazard Codes
- C,F
- Risk Statements
- 10-34
- Safety Statements
- 16-26-36/37/39-45
- RIDADR
- UN 2920 8/PG 2
- WGK Germany
- 3
- F
- 10-21
- Hazard Note
- Flammable/Corrosive
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29310095
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
N-Bromosuccinimide Price
- Product number
- 230235
- Product name
- Diphenylphosphinic chloride
- Purity
- 98%
- Packaging
- 10g
- Price
- $75.4
- Updated
- 2024/03/01
- Product number
- 230235
- Product name
- Diphenylphosphinic chloride
- Purity
- 98%
- Packaging
- 50g
- Price
- $296
- Updated
- 2024/03/01
- Product number
- C1415
- Product name
- Diphenylphosphinic Chloride
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $121
- Updated
- 2024/03/01
- Product number
- A11721
- Product name
- Diphenylphosphinic chloride, 97+%
- Packaging
- 5g
- Price
- $36.65
- Updated
- 2024/03/01
- Product number
- A11721
- Product name
- Diphenylphosphinic chloride, 97+%
- Packaging
- 25g
- Price
- $118.65
- Updated
- 2024/03/01
Diphenylphosphinic Chloride Chemical Properties,Usage,Production
Chemical Properties
clear colorless to yellow liquid
Uses
Diphenylphosphinic chloride (Ph2POCl) is widely used as a precursor to synthesize various chiral phosphine bidentate ligands for asymmetric synthesis, in addition to several peptide coupling agents.
Application
Diphenylphosphinic chloride is a reagent that is used in the synthesis of bidentate ligands and peptide coupling agents. It is used as flame retardants. It also act as pharmaceutical adjuvant.
Synthesis
To an oven-dried 100 mL, a two-necked flask fitted with a reflux condenser was added Et2O (depending on the Grignard reagent solution's concentration) and POCl3. The solution was cooled in an ice-salt mixture, and a Grignard reagent solution in Et2O was slowly added. After stirring with cooling for 30 min, the reaction mixture was brought to rt and stirred for the indicated time. The mixture was then cooled in an ice-salt mixture, and the alcohol and pyridine were slowly added. Stirring with cooling for 5 min was followed by reaction at rt. The reaction was quenched after the indicated time by cooling in an ice-salt mixture and adding sat aq NH4Cl. The crude mixture was then poured into CH2Cl2, washed three times with HCl, dried, filtered, and evaporated to dryness. The excess alcohol was removed using a short-path vacuum distillation apparatus, and the resulting crude product Diphenylphosphinic Chloride was purified by column chromatography.
Diphenylphosphinic Chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Diphenylphosphinic Chloride manufacturers
- Product
- Diphenylphosphinic Chloride 1499-21-4
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-20
- Product
- Diphenylphosphinic chloride, 98% 1499-21-4
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200tons/ year
- Release date
- 2020-03-11
- Product
- Diphenylphosphinyl Chloride 1499-21-4
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2022-09-16