3-IODOBENZYL-GUANIDINE HEMISULFATE

Product Name: 3-IODOBENZYL-GUANIDINE HEMISULFATE
CAS No.: 87862-25-7
Chemical Name: 3-IODOBENZYL-GUANIDINE HEMISULFATE
Synonyms: M-IBG;MIBG sulfate;MIBG hemisulfate;MIBG HEMISULFATE SALT;Iobenguane sulfate CRS;Iobenguane Hemisulfate;Nafamostat Impurity 14;m-iodobenzylguanidine sulfate;M-IODOBENZYLGUANIDINE 1/2H2SO4;3-IODOBENZYL-GUANIDINE HEMISULFATE
CBNumber: CB8278137
Molecular Formula: C16H22I2N6O4S
Formula Weight: 648.26
MOL File: 87862-25-7.mol

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3-IODOBENZYL-GUANIDINE HEMISULFATE Property

storage temp.: 2-8°C
solubility: DMSO: 2 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml
form: A crystalline solid
color: White to off-white

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Safety

WGK Germany: 3
HS Code: 2909309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I9890
Product name: m-Iodobenzylguanidine hemisulfate salt
Purity: ≥98%(HPLCandTLC)
Packaging: 5mg
Price: $148
Updated: 2024/03/01

Sigma-Aldrich

Product number: I9890
Product name: m-Iodobenzylguanidine hemisulfate salt
Purity: ≥98% (HPLC and TLC)
Packaging: 25MG
Price: $301.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: I0328000
Product name: Iobenguane sulfate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: I0328000
Price: $220
Updated: 2024/03/01

Cayman Chemical

Product number: 19998
Product name: m-Iodobenzylguanidine (hemisulfate)
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 19998
Product name: m-Iodobenzylguanidine (hemisulfate)
Packaging: 5mg
Price: $93
Updated: 2024/03/01

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3-IODOBENZYL-GUANIDINE HEMISULFATE Chemical Properties,Usage,Production

Description

m-Iodobenzylguanidine (MIBG) is an analogue of norepinephrine with anticancer activity. It inhibits cell growth in a panel of human and mouse leukemia, fibrosarcoma, melanoma, and neuroblastoma cell lines when used at a concentration of 20 μg/ml and reduces clonogenic survival of L1210 leukemia cells in a concentration-dependent manner. MIBG increases survival in N₁E155 and L1210 mouse xenograft models when administered at doses of 40 and 20 mg/kg, respectively. It selectively accumulates in chromaffin tissues and tumors and formulations containing radiolabeled forms of MIBG have been used as imaging agents in the diagnosis and treatment of neuroendocrine tumors. MIBG also inhibits ADP-ribose linkage to membrane proteins in turkey erythrocyte membranes.

Chemical Properties

Colourless to off-white solid

Uses

m-Iodobenzylguanidine Hemisulfate?can be used to demethylate and oxidize membrane-associated DNA. It has also been employed to develop a cell-based high-throughput screening assay to identify anti-hepatitis C virus compounds.

Biochem/physiol Actions

Antitumor agent which inhibits ADP ribosylation.

3-IODOBENZYL-GUANIDINE HEMISULFATE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-IODOBENZYL-GUANIDINE HEMISULFATE Suppliers

China 21 Germany 1 India 1 United States 5 Global 28

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87862-25-7, 3-IODOBENZYL-GUANIDINE HEMISULFATERelated Search:

3-IODOBENZYL-GUANIDINE HEMISULFATE

M-IBG

MIBG HEMISULFATE SALT

M-IODOBENZYLGUANIDINE HEMISULFATE SALT

M-IODOBENZYLGUANIDINE 1/2H2SO4

Guanidine, [(3-iodophenyl)methyl]-, sulfate (2:1)

meta-Iodobenzylguanidine hemisulfate

MIBG hemisulfate

m-iodobenzylguanidine sulfate

3-IODOBENZYLGUANIDINE HEMISULPHATE

3-IODOBENZYL-GUANIDINE HEMISULFATE

Iobenguane sulfate CRS

Iobenguane Hemisulfate

MIBG sulfate

1-(3-Iodobenzyl)guanidine hemis ulfate

m-Iodo benzyl guanidine, hemisulphate, 99%

Iobenguane sulfate，m-Iodobenzylguanidine (hemisulfate)

Guanidine,[(3-iodChemicalbookophenyl)methyl]-,sulfate(2:1)

proliferation,survival,tumors,MIBG,Iobenguane,mono(ADP-ribosylation),Iobenguane sulfate,inhibit,cytotoxic,analogue,antitumor,Inhibitor,adrenergic

Nafamostat Impurity 14

Guanidine, N-[(3-iodophenyl)methyl]-, sulfate (2:1)

87862-25-7

C8H10IN312H2SO4