METHYL 3,5-DIIODO-4-HYDROXYBENZOATE
- Product Name
- METHYL 3,5-DIIODO-4-HYDROXYBENZOATE
- CAS No.
- 3337-66-4
- Chemical Name
- METHYL 3,5-DIIODO-4-HYDROXYBENZOATE
- Synonyms
- RARECHEM AL BF 1485;METHYL 3,5-DIIODO-4-HYDROXYBENZOATE;Methyl 4-hydroxy-3,5-diiodobenzoate;4-Hydroxy-3,5-diiodo-benzoic acid Methyl ester;Benzoic acid, 4-hydroxy-3,5-diiodo-, methyl ester
- CBNumber
- CB8279336
- Molecular Formula
- C8H6I2O3
- Formula Weight
- 403.94
- MOL File
- 3337-66-4.mol
METHYL 3,5-DIIODO-4-HYDROXYBENZOATE Property
- Melting point:
- 167-168 °C
- Boiling point:
- 328.3±42.0 °C(Predicted)
- Density
- 2.377±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 5.47±0.23(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M323513
- Product name
- Methyl4-hydroxy-3,5-diiodobenzoate
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-0039845
- Product name
- Methyl4-hydroxy-3,5-diiodobenzoate
- Purity
- 99.81%
- Packaging
- 5g
- Price
- $102
- Updated
- 2021/12/16
- Product number
- CS-0039845
- Product name
- Methyl4-hydroxy-3,5-diiodobenzoate
- Purity
- 99.81%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
- Product number
- CS-0039845
- Product name
- Methyl4-hydroxy-3,5-diiodobenzoate
- Purity
- 99.81%
- Packaging
- 10g
- Price
- $196
- Updated
- 2021/12/16
- Product number
- 3883AB
- Product name
- Methyl4-hydroxy-3,5-diiodobenzoate
- Packaging
- 5g
- Price
- $204
- Updated
- 2021/12/16
METHYL 3,5-DIIODO-4-HYDROXYBENZOATE Chemical Properties,Usage,Production
Synthesis
99-76-3
3337-66-4
General procedure for the synthesis of methyl 4-hydroxy-3,5-diiodobenzoate from methyl nipagin: Potassium iodide (2.1 eq.) was added to a 50% (v/v) aqueous solution under stirring conditions. Subsequently, a solution of acetic acid (1.0 M) containing phenol derivative S5 and sodium percarbonate (SPC) (3.8 eq.) was slowly added over 30 min. The reaction mixture was stirred continuously at 50 °C for 2.0 h under a reflux condenser. Upon completion of the reaction, the reaction mixture was cooled and slowly poured into a vigorously stirred two-phase mixture consisting of dichloromethane and saturated aqueous sodium sulfite solution. The aqueous layer was separated and extracted twice with dichloromethane. The organic layer was combined and washed with saturated aqueous sodium chloride solution. The organic layer was dried over anhydrous sodium sulfate and the solvent was removed under reduced pressure. The crude product was purified by column chromatography to afford the target product methyl 4-hydroxy-3,5-diiodobenzoate (23).
References
[1] Angewandte Chemie - International Edition, 2010, vol. 49, # 32, p. 5563 - 5566
[2] Tetrahedron, 2013, vol. 69, # 21, p. 4338 - 4352
[3] Patent: CN106632180, 2017, A. Location in patent: Paragraph 0054-0058
[4] Patent: CN106478619, 2017, A. Location in patent: Paragraph 0097; 0098
[5] Chemistry Letters, 1987, p. 2109 - 2112
METHYL 3,5-DIIODO-4-HYDROXYBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from METHYL 3,5-DIIODO-4-HYDROXYBENZOATE manufacturers
- Product
- METHYL 3,5-DIIODO-4-HYDROXYBENZOATE 3337-66-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-07-18
- Product
- Methyl 4-hydroxy-3,5-diiodobenzoate 3337-66-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 100kgs/month
- Release date
- 2021-11-23