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METHYL 3,5-DIIODO-4-HYDROXYBENZOATE

Product Name
METHYL 3,5-DIIODO-4-HYDROXYBENZOATE
CAS No.
3337-66-4
Chemical Name
METHYL 3,5-DIIODO-4-HYDROXYBENZOATE
Synonyms
RARECHEM AL BF 1485;METHYL 3,5-DIIODO-4-HYDROXYBENZOATE;Methyl 4-hydroxy-3,5-diiodobenzoate;4-Hydroxy-3,5-diiodo-benzoic acid Methyl ester;Benzoic acid, 4-hydroxy-3,5-diiodo-, methyl ester
CBNumber
CB8279336
Molecular Formula
C8H6I2O3
Formula Weight
403.94
MOL File
3337-66-4.mol
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METHYL 3,5-DIIODO-4-HYDROXYBENZOATE Property

Melting point:
167-168 °C
Boiling point:
328.3±42.0 °C(Predicted)
Density 
2.377±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
5.47±0.23(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M323513
Product name
Methyl4-hydroxy-3,5-diiodobenzoate
Packaging
250mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-0039845
Product name
Methyl4-hydroxy-3,5-diiodobenzoate
Purity
99.81%
Packaging
5g
Price
$102
Updated
2021/12/16
ChemScene
Product number
CS-0039845
Product name
Methyl4-hydroxy-3,5-diiodobenzoate
Purity
99.81%
Packaging
1g
Price
$29
Updated
2021/12/16
ChemScene
Product number
CS-0039845
Product name
Methyl4-hydroxy-3,5-diiodobenzoate
Purity
99.81%
Packaging
10g
Price
$196
Updated
2021/12/16
AK Scientific
Product number
3883AB
Product name
Methyl4-hydroxy-3,5-diiodobenzoate
Packaging
5g
Price
$204
Updated
2021/12/16
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METHYL 3,5-DIIODO-4-HYDROXYBENZOATE Chemical Properties,Usage,Production

Synthesis

99-76-3

3337-66-4

General procedure for the synthesis of methyl 4-hydroxy-3,5-diiodobenzoate from methyl nipagin: Potassium iodide (2.1 eq.) was added to a 50% (v/v) aqueous solution under stirring conditions. Subsequently, a solution of acetic acid (1.0 M) containing phenol derivative S5 and sodium percarbonate (SPC) (3.8 eq.) was slowly added over 30 min. The reaction mixture was stirred continuously at 50 °C for 2.0 h under a reflux condenser. Upon completion of the reaction, the reaction mixture was cooled and slowly poured into a vigorously stirred two-phase mixture consisting of dichloromethane and saturated aqueous sodium sulfite solution. The aqueous layer was separated and extracted twice with dichloromethane. The organic layer was combined and washed with saturated aqueous sodium chloride solution. The organic layer was dried over anhydrous sodium sulfate and the solvent was removed under reduced pressure. The crude product was purified by column chromatography to afford the target product methyl 4-hydroxy-3,5-diiodobenzoate (23).

References

[1] Angewandte Chemie - International Edition, 2010, vol. 49, # 32, p. 5563 - 5566
[2] Tetrahedron, 2013, vol. 69, # 21, p. 4338 - 4352
[3] Patent: CN106632180, 2017, A. Location in patent: Paragraph 0054-0058
[4] Patent: CN106478619, 2017, A. Location in patent: Paragraph 0097; 0098
[5] Chemistry Letters, 1987, p. 2109 - 2112

METHYL 3,5-DIIODO-4-HYDROXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 3,5-DIIODO-4-HYDROXYBENZOATE Suppliers

China 47 Germany 1 India 3 Sweden 1 United States 5 Global 57
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from METHYL 3,5-DIIODO-4-HYDROXYBENZOATE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
METHYL 3,5-DIIODO-4-HYDROXYBENZOATE 3337-66-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-18
Shanghai Rlavie Technology Co ltd
Product
Methyl 4-hydroxy-3,5-diiodobenzoate 3337-66-4
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
100kgs/month
Release date
2021-11-23

3337-66-4, METHYL 3,5-DIIODO-4-HYDROXYBENZOATERelated Search:

3,5-DIIODO-4(4'-METHOXYPHENOXY)BENZOIC ACID METHYL ESTER METHYL 3,5-DIIODO-4-METHOXYBENZOATE METHYL 3,5-DIIODO-4-HYDROXYBENZOATE 3,5-DIIODO-4-(4-ACETOXYPHENYLMETHOXY)-BENZOIC ACID METHYL ESTER RARECHEM AL BI 1485

  • METHYL 3,5-DIIODO-4-HYDROXYBENZOATE
  • RARECHEM AL BF 1485
  • Methyl 4-hydroxy-3,5-diiodobenzoate
  • 4-Hydroxy-3,5-diiodo-benzoic acid Methyl ester
  • Benzoic acid, 4-hydroxy-3,5-diiodo-, methyl ester
  • 3337-66-4