1,3-BENZOXAZOL-6-AMINE
- Product Name
- 1,3-BENZOXAZOL-6-AMINE
- CAS No.
- 177492-52-3
- Chemical Name
- 1,3-BENZOXAZOL-6-AMINE
- Synonyms
- benzo[d]oxazol-6-amine;6-BenzoxazolaMine;6-AMINO-BENZOXAZOLE;Benzooxazol-6-ylamine;6-Aminobenzoxazole,95%;1,3-BENZOXAZOL-6-AMINE;6-Amino-1,3-benzoxazole
- CBNumber
- CB8280376
- Molecular Formula
- C7H6N2O
- Formula Weight
- 134.14
- MOL File
- 177492-52-3.mol
1,3-BENZOXAZOL-6-AMINE Property
- Melting point:
- 88 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- Solid
- color
- Orange to brown
- Water Solubility
- Slightly soluble in water.
- Sensitive
- Air Sensitive
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38-36-22
- Safety Statements
- 22-26-36/37/39
- RIDADR
- 2811
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- CDS013806
- Product name
- 1,3-benzoxazol-6-amine
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 250 mg
- Price
- $107
- Updated
- 2025/07/31
- Product number
- B130008
- Product name
- 6-Benzoxazolamine
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 043883
- Product name
- 1,3-Benzoxazol-6-amine
- Purity
- 97%
- Packaging
- 500mg
- Price
- $25
- Updated
- 2021/12/16
- Product number
- W3873
- Product name
- 6-Aminobenzoxazole
- Packaging
- 250mg
- Price
- $27
- Updated
- 2021/12/16
- Product number
- 043883
- Product name
- 1,3-Benzoxazol-6-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
1,3-BENZOXAZOL-6-AMINE Chemical Properties,Usage,Production
Uses
6-Aminobenzoxazole is used as pharmaceutical intermediate.
Definition
ChEBI: 6-Amino-benzoxazole is a benzoxazole.
Synthesis
17200-30-5
177492-52-3
GENERAL METHOD: 6-nitro-1,3-benzoxazole (6.13 mmol) was dissolved in ethanol (30 mL) and 10% Pd/C catalyst was added (the amount of catalyst was 20% of the mass of 6-nitro-1,3-benzoxazole). The mixture was placed in a Parr hydrogenation unit and the hydrogenation reaction was carried out at 50 psi H?(g) pressure overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under vacuum to remove the solvent. The crude product was purified by fast column chromatography using a 30%-40% ethyl acetate/hexane gradient elution to give pure 6-aminobenzoxazole.
References
[1] ACS Catalysis, 2015, vol. 5, # 3, p. 1526 - 1529
[2] Molecules, 2014, vol. 19, # 1, p. 925 - 939
[3] Collection of Czechoslovak Chemical Communications, 1996, vol. 61, # 2, p. 268 - 275
[4] Collection of Czechoslovak Chemical Communications, 1996, vol. 61, # 3, p. 371 - 380
[5] Chemical Communications, 2011, vol. 47, # 39, p. 10972 - 10974
1,3-BENZOXAZOL-6-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
1,3-BENZOXAZOL-6-AMINE Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
- Tel
- --
- Fax
- --
- enquiries@keyorganics.ltd.uk
- Country
- United Kingdom
- ProdList
- 6663
- Advantage
- 50
View Lastest Price from 1,3-BENZOXAZOL-6-AMINE manufacturers
- Product
- 1,3-BENZOXAZOL-6-AMINE 177492-52-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-30