7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE

Product Name: 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE
CAS No.: 17771-33-4
Chemical Name: 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE
Synonyms: 7-hydroxy-2,2-dimethyl-4-chromanone;2,2-Dimethyl-7-hydroxychroman-4-one;7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE;7-HYDROXY-2,2-DIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE;7-Hydroxy-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one;2,3-Dihydro-7-hydroxy-2,2-dimethyl-4H-1-benzopyran-4-one;2,2-Dimethyl-7-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2,2-dimethyl-
CBNumber: CB8281656
Molecular Formula: C11H12O3
Formula Weight: 192.21
MOL File: 17771-33-4.mol

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7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Property

Melting point:: 172 °C(Solv: ethanol (64-17-5))
Boiling point:: 354.3±42.0 °C(Predicted)
Density: 1.196±0.06 g/cm3(Predicted)
pka: 7.75±0.40(Predicted)
form: Solid
color: Off-white to pink

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Safety

HazardClass: IRRITANT
HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: B444368
Product name: 7-hydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one
Packaging: 250mg
Price: $240
Updated: 2021/12/16

Matrix Scientific

Product number: 064962
Product name: 7-Hydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one
Packaging: 500mg
Price: $144
Updated: 2021/12/16

Matrix Scientific

Product number: 064962
Product name: 7-Hydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one
Packaging: 5g
Price: $495
Updated: 2021/12/16

AK Scientific

Product number: 5940AD
Product name: 7-Hydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one
Packaging: 5g
Price: $718
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0114305
Product name: 7-HYDROXY-2,2-DIMETHYL-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE
Purity: 95.00%
Packaging: 1G
Price: $808.89
Updated: 2021/12/16

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7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Chemical Properties,Usage,Production

Uses

7-Hydroxy-2,2-dimethyl-4-chromanone (compound 41) is an inhibitor of DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule 3 grabbing non-integrin), with an IC50 of 4.66 mM[1]. DC-SIGN is the C-type lectin receptor presenting on the surface of both macrophages and dendritic cells[2].

References

[1] Wang J, et al. Negative regulation of Toll-like receptor signaling pathway. Microbes Infect. 2009 Mar;11(3):321-7. DOI:10.1016/j.micinf.2008.12.011
[2] Aaftaab Sethi, et al. Non-carbohydrate strategies to inhibit lectin proteins with special emphasis on galectins. Eur J Med Chem. 2021 Oct 15:222:113561. DOI:10.1016/j.ejmech.2021.113561

7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE Suppliers

China 23 India 1 United Kingdom 2 United States 5 Global 31

Combi-Blocks Inc.

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Matrix Scientific

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Waterstone Technology, LLC

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Ryan Scientific, Inc.

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Aagile Labs Division of Tyger Scientific

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17771-33-4, 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONERelated Search:

2,2-DIMETHYL-CHROMAN-4-ONE 6,7-DIMETHOXY-2,2-DIMETHYL-4-CHLOROMANONE 7-HYDROXY-2,2,8-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE 7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE 2,2-BIS(TRIFLUOROMETHYL)-7-METHOXYCHROMANE-4-ONE 2-Butenal, 2-methyl-4-[3a,4,5,7-tetrahydro-8-hydroxy-3,3,11,11-tetramethyl-13-(3-methyl-2-butenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-, [1R-[1alpha,1(Z),3abeta,5alpha,14aS*]]- GARCINOLIC ACID; TRANS-(SH) 7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE 2,2-DIMETHYL-7-PROPOXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE 6-(TERT-BUTYL)-7,8-DIHYDROXY-2,2-DIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE GAMBOGIC ACID 5,7-DIMETHOXY-2,2-DIMETHYL-CHROMAN-4-ONE 5,7-dihydroxy-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one

2,2-Dimethyl-7-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one

2,2-Dimethyl-7-hydroxychroman-4-one

2,3-Dihydro-7-hydroxy-2,2-dimethyl-4H-1-benzopyran-4-one

4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2,2-dimethyl-

7-hydroxy-2,2-dimethyl-4-chromanone

7-HYDROXY-2,2-DIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE

7-HYDROXY-2,2-DIMETHYL-CHROMAN-4-ONE

7-Hydroxy-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one

17771-33-4