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4-Cyanophenylboronic acid

Description Reference
Product Name
4-Cyanophenylboronic acid
CAS No.
126747-14-6
Chemical Name
4-Cyanophenylboronic acid
Synonyms
SWF-108;AKOS BRN-0076;CHEMBRDG-BB 3200965;RARECHEM AH PB 0209;4-Boronobenzonitrile;4-Cyanophenylboronic;4-cyanobboronic acid;4-Cyanophenylboric acid;4-Cyanophenylboronicaci;2-Cyanophenylboroic acid
CBNumber
CB8283302
Molecular Formula
C7H6BNO2
Formula Weight
146.94
MOL File
126747-14-6.mol
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4-Cyanophenylboronic acid Property

Melting point:
>350 °C (lit.)
Boiling point:
355.9±44.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO, Methanol (Slightly)
pka
7.38±0.10(Predicted)
form 
Powder
color 
White to yellow
BRN 
6593772
CAS DataBase Reference
126747-14-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-37/39-26-36
RIDADR 
UN3439
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
521418
Product name
4-Cyanophenylboronic acid
Purity
≥95%
Packaging
1g
Price
$40.38
Updated
2024/03/01
Sigma-Aldrich
Product number
521418
Product name
4-Cyanophenylboronic acid
Purity
≥95%
Packaging
10g
Price
$144.8
Updated
2024/03/01
TCI Chemical
Product number
C1778
Product name
4-Cyanophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
C1778
Product name
4-Cyanophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$45
Updated
2024/03/01
Alfa Aesar
Product number
L18007
Product name
4-Cyanobenzeneboronic acid, 98%
Packaging
1g
Price
$52.65
Updated
2024/03/01
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4-Cyanophenylboronic acid Chemical Properties,Usage,Production

Description

4-Cyanophenylboronic acid can be used for palladium catalyzed Suzuki cross-coupling reactions to synthesize 6-acryl-2,4-diamino-pyrimidines and triazines. It is used as precursor in the synthesis of inhibitors such as Tpl2 kinase inhibitors and P2X7 antagonists used in the treatment of pain. It is also a reagent used for preparation of himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents, trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark, antimalarial compounds via Suzuki cross-coupling, and deoxyuridine derivatives.

Reference

  • G. Cooke, H. A. de Cremiers, V. M. Rotello, B. Tarbit, P. E. Vandersträten, Synthesis of 6-aryl-2,4-diamino-pyrimidines and triazines using palladium catalysed Suzuki cross-coupling reactions, Tetrahedron, 2001, vol. 57, pp. 2787-2789
  • N. Ni, H. Chou, J. Wang, M. Li, C. Lu, P. C. Tai, B. Wang, Identification of boronic acids as antagonists of bacterial quorum sensing in Vibrio harveyi, Biochemical and Biophysical Research Communications, 2008, vol. 369, pp. 590-594

Chemical Properties

white to yellow powder

Uses

suzuki reaction

Uses

4-Cyanophenylboronic Acid is a reactant used in the synthesis of (AMG-8718), an inhibitor of β-site amyloid precursor protein cleaving enzyme (BACE1).

Uses

Intermediates of Liquid Crystals

4-Cyanophenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Cyanophenylboronic acid Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Junsei Chemical Co.,Ltd.
Tel
--
Fax
--
Email
eihon@junsei.co.jp
Country
Japan
ProdList
369
Advantage
58
Tosoh Finechem Corporation
Tel
--
Fax
--
Email
mail@tosoh-finechem.co.jp
Country
Japan
ProdList
72
Advantage
42
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from 4-Cyanophenylboronic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Cyanophenylboronic acid 126747-14-6
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Hebei Xinsheng New Material Technology Co., LTD.
Product
4-Cyanophenylboronic acid 126747-14-6
Price
US $35.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 Ton
Release date
2023-10-30
Hebei Xinsheng New Material Technology Co., LTD.
Product
4-Cyanophenylboronic acid 126747-14-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
30000 Kg
Release date
2023-11-30

126747-14-6, 4-Cyanophenylboronic acidRelated Search:


  • CHEMBRDG-BB 3200965
  • 4-CYANOPHENYLBORONIC ACID
  • 4-CYANOBENZENEBORONIC ACID
  • AKOS BRN-0076
  • RARECHEM AH PB 0209
  • P-CYANOPHENYLBORONIC ACID
  • Boronic acid, B-(4-cyanophenyl)-
  • BORONIC ACID, B-(4-CYANOPHENYL)-;
  • -CYANOBENZENEBORONIC ACID
  • 4-Cyanophenylboric acid
  • Boronic acid, (4-cyanophenyl)- (9CI)
  • 4-Boronobenzonitrile
  • 4-Boronobenzonitrile~4-Cyanophenylboronic acid
  • PARACYANOPHENYLBORONIC ACID
  • 4-Cyanophenylboronic Acid (contains varying amounts of Anhydride)
  • 4-Cyanophenylboronic acid ,98%
  • 4-Cyanophenylboronic acid,97%
  • 4-Cyanophenylboronic acid, 97%, May contain varying aMounts of anhydride
  • 4-Cyanophenylboronic
  • 4-Cyanophenylboronic acid , May contain varying amounts of anhydride, 97%
  • (4-cyanophenyl)boronic acid(SALTDATA: FREE)
  • B-(4-Cyanophenyl)boronic acid
  • 4-Cyanophenylboronic acid, 98%, for synthesis
  • 4-Cyanophenylboronicaci
  • SWF-108
  • 126747-14-6 4-Cyanophenylboronic acid
  • 4-Cyanophenylboronic Acid extrapure, 95%
  • 2-Cyanophenylboroic acid
  • 4-cyanobboronic acid
  • 126747-14-6
  • 12647-14-6
  • Organometallic Reagents
  • BORONIC ACID
  • Boronic Acids and Derivatives
  • Aryl
  • B (Classes of Boron Compounds)
  • Boronic Acids
  • Boronic Acid
  • Aryl
  • Organoborons
  • Boronic Acids & Esters
  • Phenyls & Phenyl-Het
  • Boronic acids
  • B (Classes of Boron Compounds)
  • Boronic Acids & Esters
  • Phenyls & Phenyl-Het
  • Boronic Acids
  • Boronic Acids and Derivatives
  • Substituted Boronic Acids
  • NITRILE
  • blocks
  • BoronicAcids
  • Carboxes
  • Boronate Ester
  • Potassium Trifluoroborate
  • bc0001