Anti-Dachshund homolog 1

Product Name: Anti-Dachshund homolog 1
Chemical Name: Anti-Dachshund homolog 1
Synonyms: Anti-Dach1;Anti-Dachshund homolog 1;Anti-DACH1 antibody produced in rabbit
CBNumber: CB82879789
Formula Weight: 0
MOL File: Mol file

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Anti-Dachshund homolog 1 Property

storage temp.: -20°C
form: buffered aqueous glycerol solution
biological source: rabbit

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Hazard and Precautionary Statements (GHS)

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Anti-Dachshund homolog 1 Chemical Properties,Usage,Production

Biological Activity

Dachshund homolog 1 (DACH1) plays a very important role in the proliferation of retinal and pituitary precursor cells, and also inhibits transforming growth factor-β (TGF-β) induced apoptosis. It acts as a repressor of TGF-β induction of AP-1 and Smad (transcription factors) signaling. It also represses those genes which are responsive to TGF-β. DACH1 binds to endogenous nuclear receptor co-repressor (NCoR) and inhibits the activation of reporter activity on promoters which are induced by Smad2 or Smad3. DACH1 regulates and blocks contact-independent growth, inhibits cyclin D1 and breast tumor growth. Basically, it is a cell fate determination factor.

Anti-Dachshund homolog 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Anti-Dachshund homolog 1 Suppliers

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Anti-Dachshund homolog 1Related Search:

Anti-Dach1

Anti-DACH1 antibody produced in rabbit

Anti-Dachshund homolog 1