ChemicalBook > CAS DataBase List > RO 25-6981 HYDROCHLORIDE
RO 25-6981 HYDROCHLORIDE
- Product Name
- RO 25-6981 HYDROCHLORIDE
- CAS No.
- 919289-58-0
- Chemical Name
- RO 25-6981 HYDROCHLORIDE
- Synonyms
- Ro 256981 HCl;Ro 25-6981 HCl;Ro 25 6981 HCl;Ro 25-6981 hydrochloride hydrate;4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol;[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride;[R-(R*,S*)]-ALPHA-(4-HYDROXYPHENYL)-BETA-METHYL-4-(PHENYLMETHYL)-1-PIPERIDINEPROPANOL HYDROCHLORIDE;[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrate
- CBNumber
- CB8289076
- Molecular Formula
- C22H30ClNO2
- Formula Weight
- 375.93
- MOL File
- 919289-58-0.mol
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RO 25-6981 HYDROCHLORIDE Property
- solubility
- H2O: 2 mg/mL
- form
- powder
- color
- white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- R7150
- Product name
- Ro 25-6981 hydrochloride hydrate
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5MG
- Price
- $179
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- R7150
- Product name
- Ro 25-6981 hydrochloride hydrate
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25MG
- Price
- $613
- Updated
- 2024/03/01
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RO 25-6981 HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
Ro 25-6981 hydrochloride hydrate has been used:
- as NR2B antagonist for microinjecting rats to study the contribution of NR2B- and NR2A-containing N-methyl-D-aspartate receptors (NMDARs) to the formation of trace and contextual memory in prefrontal cortex (PL)
- as NR2B antagonist to study the effect of the protein expression of hypoxic-ischemic injury NMDAR subunits 2A and 2B in the SVZ of neonatal rats
- to induce deleterious effects upon memory consolidation and long-term potentiation (LTP) generation in the hippocampus
Biochem/physiol Actions
Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit.
RO 25-6981 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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RO 25-6981 HYDROCHLORIDE Suppliers
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
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