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RO 25-6981 HYDROCHLORIDE

Product Name
RO 25-6981 HYDROCHLORIDE
CAS No.
919289-58-0
Chemical Name
RO 25-6981 HYDROCHLORIDE
Synonyms
Ro 256981 HCl;Ro 25-6981 HCl;Ro 25 6981 HCl;Ro 25-6981 hydrochloride hydrate;4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol;[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride;[R-(R*,S*)]-ALPHA-(4-HYDROXYPHENYL)-BETA-METHYL-4-(PHENYLMETHYL)-1-PIPERIDINEPROPANOL HYDROCHLORIDE;[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrate
CBNumber
CB8289076
Molecular Formula
C22H30ClNO2
Formula Weight
375.93
MOL File
919289-58-0.mol
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RO 25-6981 HYDROCHLORIDE Property

solubility 
H2O: 2 mg/mL
form 
powder
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R7150
Product name
Ro 25-6981 hydrochloride hydrate
Purity
≥98% (HPLC), powder
Packaging
5MG
Price
$179
Updated
2024/03/01
Sigma-Aldrich
Product number
R7150
Product name
Ro 25-6981 hydrochloride hydrate
Purity
≥98% (HPLC), powder
Packaging
25MG
Price
$613
Updated
2024/03/01
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RO 25-6981 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Ro 25-6981 hydrochloride hydrate has been used:

  • as NR2B antagonist for microinjecting rats to study the contribution of NR2B- and NR2A-containing N-methyl-D-aspartate receptors (NMDARs) to the formation of trace and contextual memory in prefrontal cortex (PL)
  • as NR2B antagonist to study the effect of the protein expression of hypoxic-ischemic injury NMDAR subunits 2A and 2B in the SVZ of neonatal rats
  • to induce deleterious effects upon memory consolidation and long-term potentiation (LTP) generation in the hippocampus

Biochem/physiol Actions

Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit.

RO 25-6981 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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RO 25-6981 HYDROCHLORIDE Suppliers

China 6 Switzerland 1 United States 3 Global 10
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32159
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19881
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87

919289-58-0, RO 25-6981 HYDROCHLORIDERelated Search:

1-Piperidinepropanol

  • [R-(R*,S*)]-ALPHA-(4-HYDROXYPHENYL)-BETA-METHYL-4-(PHENYLMETHYL)-1-PIPERIDINEPROPANOL HYDROCHLORIDE
  • 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol
  • [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride
  • [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrate
  • Ro 25-6981 hydrochloride hydrate
  • Ro 25 6981 HCl
  • Ro 256981 HCl
  • Ro 25-6981 HCl
  • 919289-58-0
  • C22H29NO2HCl
  • Cell Signaling and Neuroscience
  • Ionotropic Glutamate Receptor Modulators
  • Ion Channels
  • Ligand-Gated Ion Channels
  • BioChemical
  • Cell Biology
  • Glutamate receptor