ChemicalBook > CAS DataBase List > 8-Anilino-1-naphthalenesulfonic acid

8-Anilino-1-naphthalenesulfonic acid

Product Name
8-Anilino-1-naphthalenesulfonic acid
CAS No.
82-76-8
Chemical Name
8-Anilino-1-naphthalenesulfonic acid
Synonyms
ANS;PHENYL PERI ACID;1,8-ANS;ANSA;1-ANILINONAPHTHALENE-8-SULFONIC ACID;PHENYL ACID;ANSA/1,8-ANS;N-PHENYL PERI ACID;fluorescent probes;PHENYL PERI ACID AND SALTS
CBNumber
CB8289935
Molecular Formula
C16H13NO3S
Formula Weight
299.34
MOL File
82-76-8.mol
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8-Anilino-1-naphthalenesulfonic acid Property

Melting point:
215-217 °C (dec.)(lit.)
Density 
1.409±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMF: soluble50mg/mL
pka
0.19±0.40(Predicted)
form 
Powder
color 
Dark green to brown to black
Merck 
13,664
BRN 
1843887
InChI
InChI=1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)
InChIKey
FWEOQOXTVHGIFQ-UHFFFAOYSA-N
SMILES
C1(S(O)(=O)=O)=C2C(C=CC=C2NC2=CC=CC=C2)=CC=C1
CAS DataBase Reference
82-76-8(CAS DataBase Reference)
EPA Substance Registry System
8-Anilino-1-naphthalenesulfonic acid (82-76-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36-36/37/38
Safety Statements 
26-36
WGK Germany 
-
TSCA 
Yes
HS Code 
29214980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A1028
Product name
8-Anilino-1-naphthalenesulfonic acid
Purity
≥97% (HPLC)
Packaging
5g
Price
$64.1
Updated
2024/03/01
Sigma-Aldrich
Product number
A1028
Product name
8-Anilino-1-naphthalenesulfonic acid
Purity
≥97% (HPLC)
Packaging
25g
Price
$177
Updated
2024/03/01
TCI Chemical
Product number
A0472
Product name
8-Anilino-1-naphthalenesulfonic Acid
Purity
>95.0%(HPLC)(T)
Packaging
25g
Price
$85
Updated
2024/03/01
Alfa Aesar
Product number
J65332
Product name
8-Anilinonaphthalene-1-sulfonic acid, 95%
Packaging
5g
Price
$41.8
Updated
2024/03/01
Alfa Aesar
Product number
J65332
Product name
8-Anilinonaphthalene-1-sulfonic acid, 95%
Packaging
25g
Price
$89.65
Updated
2024/03/01
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8-Anilino-1-naphthalenesulfonic acid Chemical Properties,Usage,Production

Description

1,8-ANS is a fluorescent dye that binds with high affinity to hydrophobic surfaces of proteins. 1,8-ANS has an excitation maximum of 350 nm. It has an emission maximum of 520 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FABP2) it has emission maxima of 468-477 nm. 1,8-ANS binds to low polarity regions of protein surfaces making it well suited for determining the affinity of hydrophobic ligands to their corresponding binding proteins, such as the binding of free fatty acids to FABPs. 1,8-ANS binds to FABP2 with a Kd value of approximately 9.7 μM at 24.5°C.

Chemical Properties

green needles

Uses

Intermediate of dyestuff

Uses

8-Anilino-1-naphthalenesulfonic Acid is used as a fluorescent probe to identify hydrophobic sites. Dyes and metabolites.

Definition

CHEBI:8-anilinonaphthalene-1-sulfonic acid is a naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8. It has a role as a fluorescent probe. It is an aminonaphthalene and a naphthalenesulfonic acid.

Biotechnological Applications

8-Anilino-1-naphthalenesulfonic acid is a fluorescent dye with high affinity towards hydrophobic surfaces of proteins. It is useful for determining the affinity of hydrophobic ligands to their corresponding binding proteins. 8-Anilino-1-naphthalenesulfonic acid undergoes a blue shift and fluorescence increases when it binds to non-polar regions of a protein surface or membranes. Used as a probe to monitor protein-folding.

8-Anilino-1-naphthalenesulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8-Anilino-1-naphthalenesulfonic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
8-Anilino-1-naphthalenesulfonic acid 82-76-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
50kgs/month
Release date
2021-10-28
Hebei Weibang Biotechnology Co., Ltd
Product
8-Anilino-1-naphthalenesulfonic acid 82-76-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-24
Hebei Mojin Biotechnology Co.,Ltd
Product
8-Anilino-1-naphthalenesulfonic acid 82-76-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-05-24

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